Michael C. Pirrung - Böcker

The field of combinatorial chemistry has seen tremendous growth over the past decade, with a prominence that suggests it will have a continuing impact.

Volume 24 in the Tetrahedron Organic Chemistry Series represents new approaches to solving problems in chemical reactivity and function. Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the field.

The textbook includes exercises and worked problems which can provide more independent learning experiences and can also be used by an instructor leading a class on this topic.

This volume has been written with the advanced undergraduate and graduate student in mind.

Concept-based Includes exercises Suitable for self-study

The field of combinatorial chemistry has seen tremendous growth over the past decade, with a prominence that suggests it will have a continuing impact.

Volume 24 in the Tetrahedron Organic Chemistry Series represents new approaches to solving problems in chemical reactivity and function. Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the field.

The textbook includes exercises and worked problems which can provide more independent learning experiences and can also be used by an instructor leading a class on this topic. This volume has been written with the advanced undergraduate and graduate student in mind.

Making the main concepts of the field of molecular diversity and combinatorial chemistry accessible to non-specialists Written specifically for the advanced undergraduate student or graduate student An excellent guide to the conceptual framework of the field

Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author's popular 2007 work, Synthetic Organic Chemist's Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions.

The book maintains the useful organization of the author's earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product.

From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process.

Contains practical information for every part of the process that are coupled with engaging, real-world examples Presents useful guidance for conducting literature searches, handling and preparing reagents, working up the reaction, and identifying the product Presents valuable coverage of conventional and microwave temperature control, paper and electronic research notebooks, eluent selection, Schlenk lines, purification methods and determination, chiral chromatography, chemical safety, and more

The past two decades have seen an explosion in research on the synthesis of sesquiterpenes, an important class of hydrocarbons commonly found in oils, resins, and balsams. Volume Eleven in The Total Synthesis of Natural Products series continues to review this dynamic area of chemistry. It features systematic, A-to-Z coverage of sesquiterpenes synthesized between 1979-1994-a sesquidecade. Focusing on bicyclic and tricyclic compounds in sesquiterpene synthesis, this authoritative work complements Volume Ten's coverage of acyclic and monocyclic sesquiterpenes. The authors comb through the hundreds of sesquiterpene syntheses already developed, consolidating the multitude of research papers, and providing extensive references as well as author and subject indexes. To keep the presentation manageable, they emphasize literature where natural products were prepared, leaving out natural ring systems or compounds whose structures were misassigned. This volume presents multiple syntheses of the same compound in chronological order, making the various steps of the synthetic strategy easily accessible. In addition, it addresses one of the most important developments in sesquiterpene research, namely the increase in compound targets prepared in an optically active form. And while syntheses of racemates are not specifically marked, legends for synthesis schemes producing optically active compounds include their absolute configurations, signs of optical rotation, or both. An important resource for organic chemists, pharmaceutical and medicinal chemists, natural prod-ucts chemists, and biochemists, The Total Synthesis of Natural Products offers valuable insight into the structure and makeup of sesquiterpenes while serving as a practical tool for locating any of the major classes of sesquiterpene compounds. An invaluable guide for the chemist interested in natural products. Providing a fascinating, comprehensive look at sesquiterpene synthesis, Volume Eleven of The Total Synthesis of Natural Products reviews sesquiterpenes synthesized in the period 1979-1994, continuing the coverage begun with Volume Ten in the series (see below). This authoritative work: Focuses on bicyclic and tricyclic sesquiterpenes.Explains the structure and makeup of this important class of hydrocarbons.Serves as a useful, practical tool for researchers interested in locating any of the major classes of sesquiterpene compounds.Provides multiple syntheses of the same compound chronologically, clearly showing the evolution of the synthetic strategy. Also available . . .THE TOTAL SYNTHESIS OF NATURAL PRODUCTS Volume Ten, Edited by David Goldsmith. A complement to this work, Volume Ten examines compounds with acyclic and monocyclic ring structures in sesquiterpene synthesis. 1997 (0-471-59679-5) 173 pp.

The indispensable reference for the twenty-first century chemist...A fascinating and comprehensive look into one of chemistry's fastest growing specialties--sesquiterpene synthesis--Volume Ten of The Total Synthesis of Natural Products focuses on acyclic and monocyclic compounds and sheds light on the structure and makeup of this important class of hydrocarbons.A useful and practical tool for researchers interested in locating any of the major classes of sesquiterpene compounds, the author will also provide, if needed, a database to the more than 1,600 articles on sesquiterpene synthesis. The ultimate index to the newest experimental work in synthetic chemistry, this latest volume in The Total Synthesis of Natural Products series is also a glossary to the new language of chemistry in the next century.Look for the following related title in the series:THE TOTAL SYNTHESIS OF NATURAL PRODUCTS, Volume ElevenVolume Eleven continues the authoritative coverage on sesquiterpene synthesis begun in Volume Ten, examining compounds with bicyclic and tricyclic ring structures., 1997 (0-471-18874-3)The research on the synthesis of sesquiterpenes, derivatives of terpenes, a class of hydrocarbons commonly found in oils, resins, and balsams, has grown exponentially over the past fifteen years. With over 500 sesquiterpene syntheses already developed, the literature on this experimental specialty is voluminous, now encompassing over 1,600 re-search papers. Volume Ten in The Total Synthesis of Natural Products provides a systematic and comprehensive look at acyclic and monocyclic compounds in sesquiterpene synthesis.Reflecting one of the significant changes in sesquiterpene re-search, that is, the increase in compound targets prepared in an optically active form, the present volume includes their absolute configurations, signs of optical rotation, or both.This newest volume in The Total Synthesis of Natural Products series is an "A-to-Z" look at acyclic and monocyclic compounds in sesquiterpene synthesis, one of the most dynamic areas in the ongoing revolution in chemical synthesis, and is a must for the chemical professional.