Michael Olek – författare

Multiple Sclerosis: Etiology, Diagnosis, and New Treatment Strategies, provides insights to the current concepts about the evaluation, treatment and future direction of the disease. The text has an emphasis on the immunologic mechanisms that are involved in the autoimmune process and in developing treatment strategies based on these concepts. In addition to discussing current mediations for treating relapsing-remitting MS, this text focuses on recently approved medications, new indications for these medications, and those medications still in development. It also covers immunosuppressive therapy for progressive diseases as well as symptomatic therapy. Further therapies are discussed such as bone marrow transplant, combination therapies, and specific immunomodulatory treatments. The role of immunologic research is crucial in multiple sclerosis. The basic understanding of the autoimmune mechanism and its application to specific immunotherapies is explored. Immune markers, which are crucial for understanding and following the disease are also covered in detail.With the many new and current treatments studies on this disease, this book will prove to be an invaluable tool for general neurologists and primary care physicians who treat MS patients, as well as students.

A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.