Michael Otto – författare

The Clinician's Guide to Anxiety Sensitivity Treatment and Assessment provides evidence-based strategies for clinicians looking to treat, assess and better understand anxiety sensitivity in their patients. The book delivers detailed guidance on the theoretical background and empirical support for anxiety sensitivity treatment methods, assessment strategies, and how clinicians can best prepare for sessions with their clients. Bolstered by case studies throughout, it highlights anxiety sensitivity as a transdiagnostic risk factor while also looking at the importance of lower-order sensitivity factors (physical, social, cognitive) in treatment planning, implementation and evaluation.

Extensive studies have shown cognitive-behavioral therapy to be highly effective in treating anxiety disorders, improving patients’ social functioning, job performance, and quality of life. Yet every CBT clinician faces some amount of client resistance, whether in the form of “This won’t work”, “I’m too depressed”, or even “You can’t make me!” Avoiding Treatment Failures in the Anxiety Disorders analyzes the challenges presented by non-compliance, and provides disorder- and population-specific guidance in addressing the impasses and removing the obstacles that derail therapy. Making use of extensive clinical expertise and current empirical findings, expert contributors offer cutting-edge understanding of the causes of treatment complications—and innovative strategies for their resolution—in key areas, including:

Both comprehensive, and accessible, Avoiding Treatment Failures in the Anxiety Disorders will be welcomed by new and seasoned clinicians alike. The window it opens onto this class of disorders, plus the insights into how and why this treatment works, will also be of interest to those involved in clinical research.

Bacterial infections affect world health today as a leading cause of morbidity and mortality. Pathogenic bacteria routinely command a broad spectrum of niches in the human host, making an understanding of pathogenesis mechanisms crucial to the development of prophylactics and treatment for bacterial diseases. A variety of in vitro methods, in vivo animal model systems and cutting-edge genomics assays have arisen in the effort to study bacterial pathogenesis and identify potential therapeutic targets. In Bacterial Pathogenesis, in-depth methods and state-of-the-art protocols are presented for investigating specific mechanisms of pathogenesis for a wide range of bacteria. This invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections. Up-to-date molecular typing methods for Staphylococcus aureus and a new model of streptococcal pharyngitis in non-human primates are also included. Bacterial Pathogenesis will prove an invaluable collection for microbiologists, immunologists, cell biologists and infectious disease clinicians - and indispensable to all science researchers interested in studying pathogenic bacteria and related disease processes.