Ming Zhao - Böcker

The definitive compendium of bioassay procedures and applications A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models. Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories. Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students. Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which: Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer’s, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areasCovers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity—a particularly significant consideration in the development of safe and tolerable medicationsHighlights clinically relevant methods, ideas, and techniques to support any ­pharmaceutical researcherSuggests guidelines and systems to enhance communication between ­pharmacologists, chemists, and biologistsProvides an informative analysis of pharmaceutical bioassay technologies and lab applications

In the dawning era of Intelligent Computing and Big-data Services, security issues will be an important consideration in promoting these new technologies into the future. This book presents the proceedings of the 2017 International Conference on Security with Intelligent Computing and Big-data Services, the Workshop on Information and Communication Security Science and Engineering, and the Workshop on Security in Forensics, Medical, and Computing Services and Applications. The topics addressed include: Algorithms and Security Analysis, Cryptanalysis and Detection Systems, IoT and E-commerce Applications, Privacy and Cloud Computing, Information Hiding and Secret Sharing, Network Security and Applications, Digital Forensics and Mobile Systems, Public Key Systems and Data Processing, and Blockchain Applications in Technology. The conference is intended to promote healthy exchanges between researchers and industry practitioners regarding advances in the state of art of these security issues. The proceedings not only highlight novel and interesting ideas, but will also stimulate interesting discussions and inspire new research directions.