Mingjie Li – författare

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system.

Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system.- Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders- Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing- Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

The compendium summarizes the seismic exploration history, geophysical exploration technology progress, application and exploration results of foreland basins and foreland thrust belts in central and western China.The volume highlights the latest progress and exploration results of theories and methods in foreland thrust belts such as Kuqa in Tarim basin, Yingxiongling in Qaidam basin and Longmenshan in Sichuan basin. The technologies presented, such as wide azimuth and high-density 3D seismic acquisition and processing technology, anisotropic depth domain seismic processing technology, theoretical multi-information comprehensive structural modeling technology, multi-dimensional data fracture detection technology, etc, are widely used in complex areas such as foreland thrust belt.This highly illustrated and readable reference text benefits professionals, researchers, teachers and graduate students majoring in oil and gas exploration and development.

This book highlights the rapidly emerging field of solution-processed halide perovskite lasers. These amazing materials not only possess exceptional photovoltaic properties, but are also outstanding optical gain media. Halide perovskites are the latest member of solution-processed optical gain media, joining organics and traditional semiconductor colloidal quantum dots. Amplified spontaneous emission and lasing have been demonstrated in various halide perovskite configurations and nanostructures with wavelengths tunable over the visible and infrared wavelengths (400–1000 nm).This book provides comprehensive information on perovskite lasing, starting with some fundamentals of lasers and their basic operating principles. Unambiguous methods for identifying lasing light emission are presented, while the basic optoelectronic properties of perovskite materials are also discussed, with an emphasis on their photophysics, using ultrafast optical spectroscopy techniques. The viabilityof perovskites as a gain media within a suitable resonator, as well as the characterization methods for optical gain, are highlighted. The book closes with a discussion on the remaining challenges (such as electrical driven lasing and material stabilities) that need to be tackled, and the future of this new family of lasers.