Mohamed Salih – författare
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2 produkter
2 produkter
E-bok
PDF, Engelska, 201616 kr
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Research Paper (postgraduate) from the year 2016 in the subject Biology - Miscellaneous, , language: English, abstract: This is a research work on vaccination against Dengue Virus. The text mainly represents the findings in tables. Dengue virus is the kind of virus responsible for one of the most aggressive reemerging infections that threaten about half of the world's population. Despite of the high mortality and the fast dispersing of this infection, a licensed vaccine that protects against all of its serotypes is still elusive up to date. In this study, all envelope proteins (E proteins) of various Dengue virus variants from different geographical regions belonging to the four Dengue virus serotypes and representing all of what is available in NCBI till June 2016 were retrieved. Alignment of the envelope protein was conducted, and concluded that 100% conservancy would be hardly possible. IEDB analysis resource has been used to predict B and T cell epitopes and to determine their conservancy level, as well as to calculate the population coverage of T cell epitopes. Predicted epitopes with high conservancy and scores in both B and T cell epitopes predicting tools were proposed as international therapeutic vaccine candidate with an expectation of further in vitro and in vivo confirmations. This study provided a novel predicted tetravalent multi-epitope peptide vaccine against Dengue virus which could prompt vaccine development of the highly mortal disease.
Häftad, Engelska, 2012
1 082 kr
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The Organization for Social Science Research in Eastern and Southern Africa (OSSREA) is a network of social scientists in the sub-region established in 1980. Its main objectives are to encourage and promote interest; to engage in collaborative research; to facilitate scholarly exchange of ideas and publication between individuals and institutions engaged in the study and research in the social sciences. OSSREA also aims to promote the training of social scientists from the sub-region in the study of and research in the social sciences and to encourage establishment of institutions dedicated to this goal. In pursuance of and consistent with its objectives, OSSREA established a fund to provide research grants and training fellowships to social scientists from the sub-region. Every year OSSREA offers, on a competitive basis, two limited types of research grants: the first on topics related to the social sciences in general and the second on gender issues in particular. The grants assist the social scientists to conduct field research in an eastern or southern African country, society, institutions, sector, or problem area. The objectives of the social science competition are intended to encourage and promote upcoming scholars from the sub-region to conduct research in the social, economic, political or other problems. Moreover, it aims to strengthen and raise the capacity of faculty members and students in field research, and promote the subsequent availability of research fmdings for teaching as well as to inform individuals and institutions.