Mohd. Sayeed Akhtar – författare

This new volume highlights the latest strides made in the fields of agricultural biotechnology, encompassing topics from molecular biology, genetic engineering, proteomics, molecular docking, and drug delivery. The book reports on biotechnological methods to improve plant tolerance to such stresses as waterlogging and drought. It discusses ways to enhance signaling and regulatory pathways between plants and microbial communities and considers agroecosystem diversity and how it affects maintenance of soil and environmental health. Recent advances in the use of bionanotechnology for bioremediation are described, such as the use of nanobiosensors to detect environmental pollution. A range of other technological applications for solutions to environmental pollution are also reviewed.

This new volume highlights the latest strides made in the fields of agricultural biotechnology, encompassing topics from molecular biology, genetic engineering, proteomics, molecular docking, and drug delivery. The book reports on biotechnological methods to improve plant tolerance to such stresses as waterlogging and drought. It discusses ways to enhance signaling and regulatory pathways between plants and microbial communities and considers agroecosystem diversity and how it affects maintenance of soil and environmental health. Recent advances in the use of bionanotechnology for bioremediation are described, such as the use of nanobiosensors to detect environmental pollution. A range of other technological applications for solutions to environmental pollution are also reviewed.

The interactions between the plant, soil and microbes are complex in nature. Events may be antagonistic, mutualistic or synergistic, depending upon the types of microorganisms and their association with the plant and soil in question. Multi-trophic tactics can therefore be employed to nourish plants in various habitats and growth conditions. Understanding the mechanisms of these interactions is thus highly desired in order to utilize the knowledge in an ecofriendly and sustainable way. This holistic approach to crop improvement may not only resolve the upcoming food security issues, but also make the environment greener by reducing the chemical inputs. Plant, soil and microbe, Volume 1: Implications in Crop Science, along with the forthcoming Volume 2: Mechanisms and Molecular Interactions, provide detailed accounts of the exquisite and delicate balance between the three critical components of agronomy. Specifically, these two titles focus on the basis of nutrient exchange between the microorganisms and the host plants, the mechanism of disease protection and the recent molecular details emerged from studying this multi-tropic interaction. Together they aim to provide a solid foundation for the students, teachers, and researchers interested in soil microbiology, plant pathology, ecology and agronomy.

The interactions between the plant, soil, and microbes are very complex in nature and may be antagonistic, mutualistic, or synergistic, depending upon the types of microorganisms and their association with the plant and soil. The multi-trophictactics are involved in these types of interactions to nourish the plants in various habitats and conditions. Understanding the mechanisms of these interactions is highly desired to utilize the knowledge in such an eco-friendly and sustainable way, which may not only resolve the upcoming food security issues but also make the environment green by reducing the chemical inputs. Plant, Soil and Microbes: Mechanisms and Molecular Interactions, along with the recently published Plant, Soil and Microbes: Implications in Crop Science, provide detailed accounts of the exquisite and delicate balance between the three critical components of agronomy. Specifically, these two titles focus on the basis of nutrient exchange between the microorganisms and thehost plants, the mechanism of disease protection and the recent molecular details emerged from studying this multitropic interaction. Together they provide a solid foundation for the students, teachers, and researchers interested in soil microbiology, plant pathology, ecology and agronomy.

This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivatives offering safe and effective treatment and management for several types of cancer.

Plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their value in the treatment of cancer and various other infectious diseases, and several common anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants.

Unfortunately, many of these anticancer plants have become endangered due to ruthless and irresponsible harvesting practices. Hence, there is a need to conserve these species and to propagate them on a large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology could be adopted to produce these anticancer compounds without the need for cultivation. A better grasp and continuing exploration of these isolated molecules and products could provide a powerful alternative means of reducing cancer risk.

“Anticancer Plants: Volume 3, Clinical Trials and Nanotechnology” provides a timely review of concepts and experimental data on the application of anticancer plants and their compounds in clinical trials, and on the use of nanotechnology in cancer therapy.

This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.