Mohd. Sayeed Akhtar – författare

This new volume highlights the latest strides made in the fields of agricultural biotechnology, encompassing topics from molecular biology, genetic engineering, proteomics, molecular docking, and drug delivery. The book reports on biotechnological methods to improve plant tolerance to such stresses as waterlogging and drought. It discusses ways to enhance signaling and regulatory pathways between plants and microbial communities and considers agroecosystem diversity and how it affects maintenance of soil and environmental health. Recent advances in the use of bionanotechnology for bioremediation are described, such as the use of nanobiosensors to detect environmental pollution. A range of other technological applications for solutions to environmental pollution are also reviewed.

The rhizosphere, the zone of chemical, biological, and physical influence generated by root growth andactivity, offers a favorable ecological environment for a wide variety of microorganisms and is renownedfor its high level of microbial activity. This book explores how taking advantage of the diversity andbenefits of rhizospheric microbiomes in soil and environment management can enhance soil quality andstimulate the production of defense-related compounds in various pathosystems, resulting in better planthealth. It presents an array of advancements in rhizosphere science that involve soil management, hostpathogeninteractions, nutrient mobilization, bioremediation, mechanisms and modes of action ofsignaling molecules, molecular aspects of microbial interactions, and bioformulation strategies, amongothers. The volume consolidates comprehensive information on the advanced and applied aspects ofmicrobial consortia and their role in promoting plant fitness, soil management, nutrient mobilization,bioremediation, and environmental health.

Nematodes are intriguing organisms that are members of the phylum Nematoda and are widespread around the world. These parasites can feed on a variety of decorative commercially important agricultural crops, reducing farmer income in both developed and developing nations. Although nematode disease and control strategies have been extensively studied in recent years, more research and investigation into the state of plant-nematode interactions, management strategies, and damage control mechanisms needs to be done.This new volume provides in-depth knowledge of plant-nematode interactions and delves into effective management techniques. First focusing on identification and characterization of plant parasitic nematodes using molecular techniques, the volume takes a deep look at their interactions with plants, focusing on agriculturally important crops as well as ornamental plants. It goes on to cover recent advances in disease control and management strategies of parasitic nematodes on plants and crops, focusing on biocontrol, such as plant-growth-promoting rhizobacteria (PGPR) bio-formulations and other bioformulations.

This novel two-volume compilation presents scientific knowledge pertaining to the utilization of crude drugs, encompassing data on pharmacology and phytochemistry, ethnomedical applications, as well as the influence of adulterants and substitutes on human health for the prevention, treatment, and management of diseases. Crude Drugs in Unani Medicine is divided into two volumes, with the first volume exploring both the theoretical and practical aspects of potential medicinal plants and their bioactive compounds, either used individually or in combination within drug formulations, to combat a broad spectrum of chronic ailments, such as skin diseases, liver disorders, musculoskeletal conditions, reproductive system dysfunctions, immunological aberrations, and various other health issues. The second volume focuses on the pharmacology and phytochemistry of medicinal plants and animal-derived drugs, along with their pharmacovigilance.Crude Drugs of Unani Medicine: Volume 1: Application and Utility for Human Welfare delves into the understanding and application of Unani medicine (formerly referred to as Greco-Arab medicine) as a means of cure, rehabilitation, and promotion of human well-being. In the present day, medicinal plants or their bioactive compounds provide a multitude of possibilities within the Unani system of medicine. This serves as a fundamental framework, employing rational scientific theories and holistic concepts of health and healing to ensure safe diagnostic and therapeutic methods. The vast array of chemical and structural properties exhibited by medicinal plants has also been bolstered by the evolution of crude drugs, which can be utilized individually or in combination to promote human well-being.Crude Drugs of Unani Medicine: Volume 2: Phytochemistry and Pharmacology Aspects provides a comprehensive understanding of the pharmacology, phytochemistry, and pharmacovigilance of medicinal plants utilized in the traditional Unani system of medicine. The extensive range of possibilities presented by traditional medicine enables the utilization of potential therapeutic agents in the form of standardized extracts, in conjunction with other herbs or as isolated bioactive constituents. These agents possess diverse properties such as antiparasitic, antifungal, antiviral, antibacterial, antioxidant, and anticancer activities, which can be utilized as drug treatments for various systemic disorders. Moreover, these treatments have a positive impact on human health and are considered safe for consumption.Together, these two esteemed volumes offer a comprehensive resource on the use and administration of Unani drugs for diverse medical ailments. The valuable information provided here can enhance human immunity against a range of medical conditions while also avoiding undesirable side effects.

This novel two-volume compilation presents scientific knowledge pertaining to the utilization of crude drugs, encompassing data on pharmacology and phytochemistry, ethnomedical applications, as well as the influence of adulterants and substitutes on human health for the prevention, treatment, and management of diseases. Volume 1: Application and Utility for Human Welfare explores both the theoretical and practical aspects of potential medicinal plants and their bioactive compounds, either used individually or in combination within drug formulations, to combat a broad spectrum of chronic ailments, such as skin diseases, liver disorders, musculoskeletal conditions, reproductive system dysfunctions, immunological aberrations, and various other health issues.Volume 2: Phytochemistry and Pharmacology Aspects provides a comprehensive understanding of the pharmacology, phytochemistry, and pharmacovigilance of medicinal plants utilized in the traditional Unani system of medicine. It discusses the extensive range of possibilities presented by traditional medicine that enables the utilization of potential therapeutic agents in the form of standardized extracts, in conjunction with other herbs or as isolated bioactive constituents. These agents possess diverse properties such as antiparasitic, antifungal, antiviral, antibacterial, antioxidant, and anticancer activities, which can be utilized as drug treatments for various systemic disorders.

This novel two-volume compilation presents scientific knowledge pertaining to the utilization of crude drugs, encompassing data on pharmacology and phytochemistry, ethnomedical applications, as well as the influence of adulterants and substitutes on human health for the prevention, treatment, and management of diseases.Volume 1: Application and Utility for Human Welfare explores both the theoretical and practical aspects of potential medicinal plants and their bioactive compounds, either used individually or in combination within drug formulations, to combat a broad spectrum of chronic ailments, such as skin diseases, liver disorders, musculoskeletal conditions, reproductive system dysfunctions, immunological aberrations, and various other health issues.Volume 2: Phytochemistry and Pharmacology Aspects provides a comprehensive understanding of the pharmacology, phytochemistry, and pharmacovigilance of medicinal plants utilized in the traditional Unani system of medicine. It discusses the extensive range of possibilities presented by traditional medicine that enables the utilization of potential therapeutic agents in the form of standardized extracts, in conjunction with other herbs or as isolated bioactive constituents. These agents possess diverse properties such as antiparasitic, antifungal, antiviral, antibacterial, antioxidant, and anticancer activities, which can be utilized as drug treatments for various systemic disorders.

The interactions between the plant, soil and microbes are complex in nature. Events may be antagonistic, mutualistic or synergistic, depending upon the types of microorganisms and their association with the plant and soil in question. Multi-trophic tactics can therefore be employed to nourish plants in various habitats and growth conditions. Understanding the mechanisms of these interactions is thus highly desired in order to utilize the knowledge in an ecofriendly and sustainable way. This holistic approach to crop improvement may not only resolve the upcoming food security issues, but also make the environment greener by reducing the chemical inputs. Plant, soil and microbe, Volume 1: Implications in Crop Science, along with the forthcoming Volume 2: Mechanisms and Molecular Interactions, provide detailed accounts of the exquisite and delicate balance between the three critical components of agronomy. Specifically, these two titles focus on the basis of nutrient exchange between the microorganisms and the host plants, the mechanism of disease protection and the recent molecular details emerged from studying this multi-tropic interaction. Together they aim to provide a solid foundation for the students, teachers, and researchers interested in soil microbiology, plant pathology, ecology and agronomy.

The interactions between the plant, soil, and microbes are very complex in nature and may be antagonistic, mutualistic, or synergistic, depending upon the types of microorganisms and their association with the plant and soil.

The interactions between the plant, soil and microbes are complex in nature. Plant, soil and microbe, Volume 1: Implications in Crop Science, along with the forthcoming Volume 2: Mechanisms and Molecular Interactions, provide detailed accounts of the exquisite and delicate balance between the three critical components of agronomy.

The interactions between the plant, soil, and microbes are very complex in nature and may be antagonistic, mutualistic, or synergistic, depending upon the types of microorganisms and their association with the plant and soil.

Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer.

Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivatives offering safe and effective treatment and management for several types of cancer.Plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their value in the treatment of cancer and various other infectious diseases, and several common anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants.Unfortunately, many of these anticancer plants have become endangered due to ruthless and irresponsible harvesting practices. Hence, there is a need to conserve these species and to propagate them on a large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology could be adopted to produce these anticancer compounds without the need for cultivation. A better grasp and continuing exploration of these isolated molecules and products could provide a powerful alternative means of reducing cancer risk.“Anticancer Plants: Volume 3, Clinical Trials and Nanotechnology” provides a timely review of concepts and experimental data on the application of anticancer plants and their compounds in clinical trials, and on the use of nanotechnology in cancer therapy.

This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types.The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities.Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.

Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer.

Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivatives offering safe and effective treatment and management for several types of cancer.Plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their value in the treatment of cancer and various other infectious diseases, and several common anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants.Unfortunately, many of these anticancer plants have become endangered due to ruthless and irresponsible harvesting practices. Hence, there is a need to conserve these species and to propagate them on a large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology could be adopted to produce these anticancer compounds without the need for cultivation. A better grasp and continuing exploration of these isolated molecules and products could provide a powerful alternative means of reducing cancer risk.“Anticancer Plants: Volume 3, Clinical Trials and Nanotechnology” provides a timely review of concepts and experimental data on the application of anticancer plants and their compounds in clinical trials, and on the use of nanotechnology in cancer therapy.

This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types.The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities.Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.

Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine.

Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine.

Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads.

Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads.

Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds and their products is considered to be suitable and safe in e.g. alternative medicine. Thus, there is an unprecedented need to meet the increasing demand for plant secondary metabolites in the flavor and fragrance, food, and pharmaceutical industries. However, it is difficult to obtain a constant quantity of compounds from the cultivated plants, as their yield fluctuates due to several factors including genotypic variations, the geography, edaphic conditions, harvesting and processing methods. Yet familiarity with these substances and the exploration of various approaches could open new avenues in their production. This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries. Accordingly, it offers a valuable resource for students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries.

This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mechanisms, such as various compatible solutes, polyamines, reactive oxygen species and antioxidant defense mechanisms, ion transport and compartmentalization of injurious ions. The exploitation of genetic variation, use of plant hormones, mineral nutrients, soil microbe interactions, and other mechanical practices are of prime importance in agriculture, and as such have been the subject of multidisciplinary research. Covering both theoretical and practical aspects, the book provides essential physiological, ecological, biochemical, environmental and molecular information as well as perspectives for future research. It is a valuable resource for students, teachers and researchers and anyone interested in agronomy, ecology, stress physiology, environmental science, crop science and molecular biology.

This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. It is a valuable resource for students, teachers and researchers and anyone interested in agronomy, ecology, stress physiology, environmental science, crop science and molecular biology.

This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mechanisms, such as various compatible solutes, polyamines, reactive oxygen species and antioxidant defense mechanisms, ion transport and compartmentalization of injurious ions. The exploitation of genetic variation, use of plant hormones, mineral nutrients, soil microbe interactions, and other mechanical practices are of prime importance in agriculture, and as such have been the subject of multidisciplinary research. Covering both theoretical and practical aspects, the book provides essential physiological, ecological, biochemical, environmental and molecular information as well as perspectives for future research. It is a valuable resource for students, teachers and researchers and anyone interested in agronomy, ecology, stress physiology, environmental science, crop science and molecular biology.

This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. It is a valuable resource for students, teachers and researchers and anyone interested in agronomy, ecology, stress physiology, environmental science, crop science and molecular biology.