Muhammad Imran – författare

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites.This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment.- Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications- Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment- Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites.

This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment.

Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers

Metal Nanoparticles for Drug Delivery and Diagnostic Applications addresses the lifecycle of metal nanoparticles, from synthesis and characterization, to applications in drug delivery and targeting. It is an important resource for those in biomaterials, nanomedicine and pharmaceutical sciences, exploring gold, silver and iron-based drug delivery systems for controlled and targeted delivery of potential drugs and genes for enhanced clinical efficacy. Nanotechnology is widely used in drug delivery due to its ability to reduce plasma fluctuation of drugs, high solubility, and efficiency, the relatively low cost of nanoscale products, and enhancement of patient comfort, hence this resource is a welcome edition to the science.

Illustrates the progression of nanoparticle therapeutics from basic research to applications Explores new opportunities and ideas for developing and improving technologies in nanomedicine and nanobiology Discusses the toxicity of different types of metal nanoparticles and how to ensure their safe use

Metal Nanoparticles for Drug Delivery and Diagnostic Applications addresses the lifecycle of metal nanoparticles, from synthesis and characterization, to applications in drug delivery and targeting. It is an important resource for those in biomaterials, nanomedicine and pharmaceutical sciences, exploring gold, silver and iron-based drug delivery systems for controlled and targeted delivery of potential drugs and genes for enhanced clinical efficacy. Nanotechnology is widely used in drug delivery due to its ability to reduce plasma fluctuation of drugs, high solubility, and efficiency, the relatively low cost of nanoscale products, and enhancement of patient comfort, hence this resource is a welcome edition to the science.- Illustrates the progression of nanoparticle therapeutics from basic research to applications- Explores new opportunities and ideas for developing and improving technologies in nanomedicine and nanobiology- Discusses the toxicity of different types of metal nanoparticles and how to ensure their safe use

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail, along with their characterization aspects and effects of their dimensions on drug delivery systems behavior in-vitro and in-vivo. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/genes for enhanced clinical efficacy.

Provides the present state of widely used lipid-based nanoparticulate delivery systems Explores how lipid-based nanocarriers improve drug delivery safety Describes the nanoformulation design and the preparation methods of lipid-based nanocarriers

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail, along with their characterization aspects and effects of their dimensions on drug delivery systems behavior in-vitro and in-vivo. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/genes for enhanced clinical efficacy.- Provides the present state of widely used lipid-based nanoparticulate delivery systems- Explores how lipid-based nanocarriers improve drug delivery safety- Describes the nanoformulation design and the preparation methods of lipid-based nanocarriers

Implementing R for Statistics provides comprehensive coverage of basic statistical concepts using this important open-source programming language tool, from installing R and RStudio, to exploring its basic structure and uses, to extending some core functions such as vectors, basic mathematical operations, and data frames. The book will help readers understand the latest advances in the R programming language, as R allows for sophisticated and elegant data visualization. Illustrated examples are an integral part of the text, carefully designed to apply the core principles illustrated in the text to emerging topics in the field.The text also focuses on exploiting the flexible and user-friendly nature of R. Basic concepts and recent advances in the field, including understanding the R basics, as well as implementing and practicing them in statistics, are also covered. This first edition is an essential text for students, lecturers, data scientists, and applied researchers in all areas of statistics, as well as in related fields such as biostatistics, health care, finance, risk management, social sciences, market research, and environmental and climate research.Introduces core statistics concepts and how to apply them using R in an accessible mannerExplains to readers the newest advances in the area of implementing R in statistics through clear and meticulously crafted examplesExplores the process of learning R from installation to package creation, employing clear steps and illustrated examplesCovers important and evolving aspects of R, such as using RStudio, managing metadata, advanced regression modeling techniques, and creating packagesIncludes updated package references to the latest R packages, incorporating up-to-date tools available in the field

Implementing R for Statistics provides comprehensive coverage of basic statistical concepts using this important open-source programming language tool, from installing R and RStudio, to exploring its basic structure and uses, to extending some core functions such as vectors, basic mathematical operations, and data frames. The book will help readers understand the latest advances in the R programming language, as R allows for sophisticated and elegant data visualization. Illustrated examples are an integral part of the text, carefully designed to apply the core principles illustrated in the text to emerging topics in the field.The text also focuses on exploiting the flexible and user-friendly nature of R. Basic concepts and recent advances in the field, including understanding the R basics, as well as implementing and practicing them in statistics, are also covered. This first edition is an essential text for students, lecturers, data scientists, and applied researchers in all areas of statistics, as well as in related fields such as biostatistics, health care, finance, risk management, social sciences, market research, and environmental and climate research. - Introduces core statistics concepts and how to apply them using R in an accessible manner- Explains to readers the newest advances in the area of implementing R in statistics through clear and meticulously crafted examples- Explores the process of learning R from installation to package creation, employing clear steps and illustrated examples- Covers important and evolving aspects of R, such as using RStudio, managing metadata, advanced regression modeling techniques, and creating packages- Includes updated package references to the latest R packages, incorporating up-to-date tools available in the field

Smart City and sensing platforms are considered some of the most significant topics in the Internet of Things (IoT). Sensors are at the heart of the IoT, and their development is a key issue if such concepts are to achieve their full potential.This book addresses the major challenges in realizing smart city and sensing platforms in the era of the IoT and the Cloud. Challenges vary from cost and energy efficiency to availability and service quality. To tackle these challenges, sensors must meet certain expectations and requirements such as size constraints, manufacturing costs and resistance to environmental factors.This book focuses on both the design and implementation aspects for smart city and sensing applications that are enabled and supported by IoT paradigms. Attention is also given to data delivery approaches and performance aspects.

This book constitutes the proceedings of the First MICCAI Challenge Multi-class Segmentation of the Aorta, AortaSeg 2024, held in conjunction with MICCAI 2024, as a virtual event, during October 2024. The 10 papers included in the book were carefully reviewed and selected from 16 submitting teams. This challenge aimed to advance the field of medical image segmentation by introducing the first large-scale, publicly available dataset for multi-class segmentation of the aorta, its branches, and clinically relevant zones in computed tomography angiography (CTA).

This book constitutes the proceedings of the First MICCAI Challenge Multi-class Segmentation of the Aorta, AortaSeg 2024, held in conjunction with MICCAI 2024, as a virtual event, during October 2024. The 10 papers included in the book were carefully reviewed and selected from 16 submitting teams. This challenge aimed to advance the field of medical image segmentation by introducing the first large-scale, publicly available dataset for multi-class segmentation of the aorta, its branches, and clinically relevant zones in computed tomography angiography (CTA).

Public transport in low-income Asian (LIA) cities fails to meet people’s mobility needs, generates high greenhouse gas (GHG) emissions and worsens social exclusion. Following successful Bus Rapid Transit (BRT) projects in Bogota and Curitibá, LIA countries promoted BRT in their large to medium-sized cities. However, the political and institutional structure distinctive to LIA cities makes their implementation difficult. This book investigates policy tensions by examining the planning and attempted implementation of BRT projects, taking Bandung and Surabaya in Indonesia as case studies. It analyses BRT to understand how power and communication gaps in institutional relationships between different actors at multiple levels of governance create conflict, and concludes that top-down policies and funding mechanisms cause tension in intergovernmental relationships. It also found that BRT solutions generated socio-political tension arising from the socio-economic realitiesand local political dynamics that shaped city structure, mobility patterns and capacity in resolving conflicts. The superimposed BRT solution generated discursive tension because conflicting discourses were not aligned with local economic, social, and environmental issues. The book highlights the need to take into consideration the vital role of local social and political actors, institutions and planning processes as they respond to and shape policies that are imposed by higher levels.

Public transport in low-income Asian (LIA) cities fails to meet people’s mobility needs, generates high greenhouse gas (GHG) emissions and worsens social exclusion. Following successful Bus Rapid Transit (BRT) projects in Bogota and Curitibá, LIA countries promoted BRT in their large to medium-sized cities. However, the political and institutional structure distinctive to LIA cities makes their implementation difficult. This book investigates policy tensions by examining the planning and attempted implementation of BRT projects, taking Bandung and Surabaya in Indonesia as case studies. It analyses BRT to understand how power and communication gaps in institutional relationships between different actors at multiple levels of governance create conflict, and concludes that top-down policies and funding mechanisms cause tension in intergovernmental relationships. It also found that BRT solutions generated socio-political tension arising from the socio-economic realitiesand local political dynamics that shaped city structure, mobility patterns and capacity in resolving conflicts. The superimposed BRT solution generated discursive tension because conflicting discourses were not aligned with local economic, social, and environmental issues. The book highlights the need to take into consideration the vital role of local social and political actors, institutions and planning processes as they respond to and shape policies that are imposed by higher levels.