Nasimul Noman - Böcker

Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologistsThis book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics.• Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC)• Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications• Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology• Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligenceEvolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students.Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.

This book delivers theoretical and practical knowledge of Genetic Algorithms (GA) for the purpose of practical applications. It provides a methodology for a GA-based search strategy with the integration of several Artificial Life and Artificial Intelligence techniques, such as memetic concepts, swarm intelligence, and foraging strategies. The development of such tools contributes to better optimizing methodologies when addressing tasks from areas such as robotics, financial forecasting, and data mining in bioinformatics.The emphasis of this book is on applicability to the real world. Tasks from application areas - optimization of the trading rule in foreign exchange (FX) and stock prices, economic load dispatch in power system, exit/door placement for evacuation planning, and gene regulatory network inference in bioinformatics - are studied, and the resultant empirical investigations demonstrate how successful the proposed approaches are when solving real-world tasks of great importance.

Consequently, EC researchers are enthusiastic about applying their arsenal for the design and optimization of deep neural networks (DNN). This book brings together the recent progress in DL research where the focus is particularly on three sub-domains that integrate EC with DL: (1) EC for hyper-parameter optimization in DNN;