Navneet Joshi - Böcker

This three-book set introduces the basic fundamentals in both engineering and life sciences required for designing an optimal bioprocess system.Bioprocess Engineering & Technology: Fundamentals, Upstream and Downstream Processing and Plant Design (Three volume set) covers upstream and downstream processes as well as practical aspects in bioprocess plant design and project engineering, process economics, IPR, and biobusiness prospects related to bioprocess engineering. The first volume introduces the reader to basics in both engineering and life sciences required for designing an optimal bioprocess system. The book encompasses life science subjects such as cell physiology, microbiology, biochemistry, and molecular biology for the benefit of engineers and contains engineering fundamentals required for life science experts which are restricted to fluid mechanics, reaction engineering, heat and mass transfer, and analytical techniques involved in bioprocess engineering. Volume 2 discusses the various cellular interventions that are required for the upstream processes in bioprocess engineering such as growth requirement of different cell types, their maintenance, and various recombinant strategies/tools available to identify and develop a cellular factory for high level synthesis of a desired product. The third volume deals with the practical aspects in bioprocess plant design, project engineering, process economics, IPR, and biobusiness prospects related to bioprocess engineering. The book also explains how productivity, efficiency and safety of process plants hinge on proper equipment functionality.The text is wide in scope and highlights the multidimensional approach for developing expertise in bioprocessing and would be a useful resource for students, researchers and professionals studying bioprocess engineering and upstream processes involved in an industrial-scale bioprocessing operation as well as entrepreneurs and managers in the business.

This book introduces the reader to basics in both engineering and life sciences required for designing an optimal bioprocess system. Bioprocess Engineering and Technology: Fundamentals integrates life science topics such as cell physiology, microbiology, biochemistry, and molecular biology with essential engineering principles, specifically targeting the needs of both engineers and life science experts. It covers engineering fundamentals relevant to bioprocess engineering, including reaction engineering, fluid mechanics, heat and mass transfer, and the analytical techniques involved in bioprocess operations. To effectively understand bioprocesses, both life scientists and process engineers must approach biological systems with a cross-disciplinary perspective. Therefore, the book begins by exploring key topics like microbiology, biochemistry, cellular metabolism, bioenergetics, molecular biology, and cellular physiology – areas that form the foundation for understanding the role of biocatalysts in product accumulation. The subsequent chapters focus on engineering principles that govern biochemical reactions, fluid, heat, and mass transport phenomena, followed by an in-depth discussion on various analytical tools involved in bioprocess engineering. This book is designed to provide a comprehensive foundation for senior undergraduate and postgraduate students, as well as researchers in bioprocess engineering, particularly for applications in industrial-scale processes.

This book discusses the various cellular interventions that are required for the upstream processes in bioprocess engineering such as growth requirement of different cell types, their maintenance, and various recombinant strategies/tools available to identify and develop a cellular factory for high-level synthesis of a desired product. Bioprocess Engineering and Technology: Upstream Process also deals with the various types of reactors, process design and development (media, conditions, mode of operation, sterilisation, selectivity), reactor design and construction, scale-up, process analytical technologies, and process control. The book examines upstream processes which include the selection of cell factories and strain engineering approaches, enzyme kinetics, growth kinetics, fermentation, downstream processing, process design, reactor design, and scale-up. It also includes case studies that will assist readers to develop the upstream processes involved in an industrial-scale bioprocess. This book is intended for students and researchers looking to develop the upstream processes involved in an industrial-scale bioprocessing operation.