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Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases, among other disease types.
Step-by-step instruction is provided around research protocols and methods discussed, along with careful attention to the ethical implications of mitochondrial transplantation research and application.
Provides an in-depth discussion of mitochondrial transplantation, considering fundamental biology, disease implications, research methods and applicationsDiscusses recent advances in the field and their meaning for future research and clinical utilityConsiders ethical dimensions of mitochondrial transplantation research and use in therapeuticsExamines mitochondrial transplantation across a range of disease types, from neurological to cardiovascular disease and ischemia