P. N. Campbell – författare

Hip resurfacing arthroplasty (HRA) using metal-on-metal bearings is an established but specialised technique in joint surgery. Based on the experience of leading experts in the field, The hip resurfacing handbook provides a comprehensive reference for all aspects of this important procedure.The first part of the book reviews and compares all the major hip resurfacing prostheses, their key design features, relevant surgical techniques and clinical results. Part two discusses clinical follow-up of the hip resurfacing patient, including pre- and post-operative examination, acoustic phenomena and rehabilitation. It also covers the use of techniques such as radiography and metal ion measurement, as well as bone scans, ultrasound, CT, MRI, PET and DEXA, to evaluate hip resurfacings. Part three reviews best practice in surgical technique, including the modified posterior and anterior approaches, as well as instrumentation, anaesthesia and revision surgery. Based on extensive retrieval studies, Part four includes examples of the main failure modes in HRA. The final part of the book includes patients'' own experiences, a comparison of HRA with total hip arthroplasty (THA), regulatory issues and relevant web sites.Comprehensive in its scope and authoritative in its coverage, The hip resurfacing handbook is a standard work for orthopaedic surgeons and all those involved in HRA.- A standard work for orthopaedic surgeons and all those involved in HRA- Reviews and compares all the major hip resurfacing prostheses, their key design features, relevant surgical techniques and clinical results- Clinical follow-up of the patient is discussed

Biology in Profile: A Guide to the Many Branches of Biology is a 20-chapter text that describes the profile and biological phenomena of selected branches of biology. Each chapter discusses the scope, growth areas, and specialties of the specific branch of biology. This book includes 20 branches of biology, such as zoology, botany, microbiology, physiology, ecology, ethology, psychology, parasitology, pharmacy, and pharmacology. Other branches covered include toxicology, nutrition, food science, endocrinology, immunology, genetics, virology, biophysics, biochemistry, and molecular biology. This book will be of value to students and other scientists who are not practicing biologists.

The Biochemistry of Foreign Compounds presents the various aspects of biochemistry of foreign compounds in relation to toxicology, pathology, and pharmacology. This book discusses the classification of foreign compounds according to usage, namely, food additives, drugs, pesticides, industrial chemicals, and natural foreign compounds. Organized into two sections encompassing 12 chapters, this book starts with the absorption and secretion of foreign compounds. This text then discusses the two phases of reaction in the metabolism of foreign compounds. Other chapters consider the rate at which each reaction proceeds wherein its relative significance may be affected by many factors that may result in changes in the pattern of metabolism and differences in toxicity. This book discusses as well the physiological factors that affect metabolism, including age, sex, pregnancy, disease, and the nutritional state of the animal. The final chapter deals with the metabolism of some of the commonly used industrial chemicals. This book is a valuable resource for biochemists, chemists, toxicologists, pharmacologists, and pathologists.

Aldosterone provides a comprehensive and detailed review of the problems that have arisen in the course of research on aldosterone, particularly with respect to their physiological roles and clinical implications. Topics covered include the biosynthesis, transport, and metabolism of aldosterone, as well as its biological activity and control of its secretion. A variety of pathological conditions, both acute and chronic, associated with aldosterone is also discussed. This volume is comprised of 10 chapters and opens with a historical background on aldosterone research, with emphasis on the discovery of the function of the adrenal cortex. The next chapter summarizes the methods suitable for the evaluation of aldosterone activity, from investigations of mineral metabolism to determination of the concentration of aldosterone or aldosterone metabolites; estimation of secretion of aldosterone; and examination of aldosterone metabolism. Subsequent chapters explore the biosynthesis, transport, and metabolism of aldosterone; secretion of aldosterone, factors affecting secretion, and how it can be controlled; pathological conditions caused by either an increase or a decrease in aldosterone secretion, including aldosteronism, Conn''s syndrome, hypoaldosteronism, and hypomineralocorticism. The therapeutic uses of aldosterone are discussed in the last chapter. This book will appeal to biologists and biochemists.

The Chromatography of Steroids details the fundamental concepts and underlying principles of laboratory techniques utilized in separating steroid mixtures. The text first covers the basic theory of chromatography, and then proceeds to tackling the chromatographic separation of steroids. Next, the selection details the techniques and apparatus employed in chromatography of steroids. Chapter IV talks about the colorimetric and radioisotopic techniques, while Chapter V deals with the structural analysis and identification of steroids by chromatography. The text also coves the typical analytical problems of steroid biochemistry. The book will be of great use to researchers who utilizes chromatographic methods in their work with steroids.

The Structure and Function of Animal Cell Components: An Introductory Text provides an introduction to the study of animal cells, specifically the structure and function of the cells. To help readers appreciate the discussions, this book first provides an introduction to the physiological and biochemical function of animal cells, which is followed by an introduction to animal cell structure. This text then presents topics on the components of the cells, such as the mitochondria and the nucleus, and processes in the cells, including protein synthesis. This selection will be invaluable to cytologists, anatomists, and pathologists, as well as to readers who have an elementary knowledge of both biochemistry and cytology.

Biochemical Approaches to Cancer focuses on biochemical approaches to cancer and covers topics ranging from the nature of carcinogens and their interactions with cell constituents to tissue composition and metabolism as affected by neoplasia. The metabolism of carbohydrates, fatty acids, proteins, and nucleic acids is also discussed, along with biochemical pharmacology. Comprised of nine chapters, this book begins with an overview of the nature of cancer, which includes basic concepts and terminology, histology, and the use of electron microscopy to study cells. The reader is then introduced to various approaches to the cancer problem; the nature of carcinogens and interactions with cell constituents; and the effect of neoplasia on tissue composition and metabolism. Subsequent chapters deal with the metabolism of carbohydrates, fatty acids, proteins, and nucleic acids. The book also considers the "control mechanisms" governing enzymic activities and their role in neoplastic transformation before concluding with an analysis of the biochemical pharmacology of anti-cancer drugs. This monograph will be useful to biochemists, oncologists, pharmacologists, research workers, and undergraduate or postgraduate students interested in the biochemistry of cancer.