Paul Klenerman – författare

The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behaviour, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called "innate" immune responses, which react very fast to infection, and "adaptive" immune responses, which have huge diversity and a capacity to recognise and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the "Immune system v2.o" -- how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behaviour, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called "innate" immune responses, which react very fast to infection, and "adaptive" immune responses, which have huge diversity and a capacity to recognise and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the "Immune system v2.o" -- how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Written primarily for mid-to-upper level undergraduates, this title provides an introduction to immunology with a focus on human health and disease.Immunology is written to act as a map for students to go on and explore, with enthusiasm, a fast-moving field. It gives insights into the molecular pathways and mechanisms that underlie the function of our immune systems in health and disease, the understanding of which supports the development of new therapeutics. Key Features· Oxford Biology Primers are the only resource to introduce prospective and current students of undergraduate-level bioscience to a range of topics from this dynamic experimental science, enticing readers to study further. · Its titles directly support two key transitions in the student journey: from school to undergraduate-level study, and from undergraduate to independent researcher. · Its modular format offers a high degree of flexibility, with teachers being able to draw on specific volumes that augment the post-16 curriculum and university lecturers being able to draw on specific volumes at different stages of the undergraduate curriculum.All titles in the series are available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support. For more information about e-books, please visit www.oxfordtextbooks.co.uk/ebooks

Very Short Introductions: Brilliant, Sharp, Inspiring The immune system is central to human health. Growing understanding of the immune system, and especially the creation of immune memory (which results in long lasting protection), have led to major breakthroughs in medicine and the design of vaccines.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. He considers how the immune system evolved, the basic rules that govern its behaviour, and the major health threats where it is important. Paul Klenerman also explains how things can go wrong when there is too little or too much immunity. The book also addresses what we learned about the immune system from the COVID-19 pandemic and how that has influenced thinking about future pandemics.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Very Short Introductions: Brilliant, Sharp, Inspiring The immune system is central to human health. Growing understanding of the immune system, and especially the creation of immune memory (which results in long lasting protection), have led to major breakthroughs in medicine and the design of vaccines.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. He considers how the immune system evolved, the basic rules that govern its behaviour, and the major health threats where it is important. Paul Klenerman also explains how things can go wrong when there is too little or too much immunity. The book also addresses what we learned about the immune system from the COVID-19 pandemic and how that has influenced thinking about future pandemics.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.