Peter J Hoskin - Böcker

Radioisotope therapy is an internal form of radiation used to treat cancer; it may be administered orally or intravenously and represents the nearest treatment option to the 'magic bullet', specifically targeting sites of disease whilst sparing surrounding normal tissues. Radioisotope therapy has an important role to play in modern medicine, particularly in the treatment of thyroid disease, neuroendocrine tumours, bone metastasis and non-Hodgkin's lymphoma. It is found in both the diagnostic setting and in therapy, but recently there has been a renaissance in the application of radioisotope unsealed sources in therapeutic indications. It is an active area of research, with the quest for new compounds that will be specific for therapeutic targets.This book is an essential, practical guide to the use of radioisotope therapy, and also includes the background and developmental biology which underpins its use. Individual tumours and diseases are explored, with specific focus given to radioisotope treatment options. The barriers to radioisotope therapy, such as ease of access, acquisition of radioisotopes, radiation protection regulations, and cost are also discussed. ABOUT THE SERIESRadiotherapy remains the major non-surgical treatment modality for the management of malignant disease, with over 50% of patients receiving treatment at some time during the management of their malignant disease. It is based on the application of the principles of applied physics, radiobiology, and tumour biology to clinical practice. Each volume in this series takes the reader through the basic principles of different types of radiotherapy, and then develops these by individual sites. This series of practical handbooks are aimed at physicians both training and practising in radiotherapy, as well as medical physicists, dosimetrists, radiographers and senior nurses.

Now in its second edition, Comprehensive Brachytherapy: Physical and Clinical Aspect presents a fully updated, detailed, and comprehensive account of the underlying physics and practice of modern brachytherapy, including the design and implementation of new technologies and techniques.Combining research and application, this foundational text provides insight into the technological and biological basis, as well as quality assurance and advanced methods. It explores clinical protocols and discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization. Alongside practical guidance for practitioners, this second edition includes brand new chapters on clinical uses, including skin brachytherapy and brachytherapy for head and neck cancers.Key Features:Provides comprehensive coverage of modern brachytherapy physicsDiscusses major technical advances in brachytherapy and provides guidance on quality assurance methodsContains new chapters dedicated to specific clinical applicationsThis easily digestible book is a core text for brachytherapy courses and will be of use and relevance to students studying both medical physics and radiation oncology. Surgical oncology specialists will also find this book of interest.

Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners.Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.