Peter M. Rothwell – författare

Inspired by a hugely successful series entitled Treating Individuals, originally published in The Lancet, this volume will become essential reading for any professional involved with performance and evaluation of trials and systematic reviews or clinical patient care. There are many books explaining the importance of evidence-based medicine and how randomised clinical trials (RCTs) and systematic reviews should be performed. However, this is the first book to tackle the apparent conflict between the importance of evidence-based decision making and the widely held view that it is often very difficult to apply the overall results of RCTs and systematic reviews to decisions about individual patients in routine clinical practice. The book brings together experienced clinicians, statisticians and trialists to focus on the two key questions that are most frequently asked by clinicians. Is the evidence relevant to my clinical practice? How can I judge whether the probability of benefit from treatment in my current patient is likely to differ substantially from the average probability of benefit reported in the relevant trial or systematic review? These questions are addressed from methodological and clinical perspectives, and potential approaches to improving the targeting of treatment are considered, with detailed reviews of several areas of medicine and surgery where useful progress has been made.

The Oxford Case Histories series provides complex, case-based learning for medical trainees undertaking their exit examinations as well as consultants wishing to undertake continuing professional development. The skills necessary for confident and competent diagnosis and successful management of complex medical problems are developed through the study of individual patients. This series offers real-life cases specifically written to help enable trainees to meet the required standard prior to being awarded a certificate of completion of training (CCT). Each volume in the series is mapped to the core curricula and includes between 40-50 cases, comprising a brief clinical history and investigations, followed by questions on differential diagnosis and management, and detailed answers with discussion. At the end of each book, cases are listed by mode of presentation, aetiology, and diagnosis for quick reference. The series covers a wide range of specialties including general surgery, geriatric medicine, and infectious disease, and is an excellent revision aid for clinicians in specialist training (MRCP and above) and consultants undertaking continuing professional development. Dr Sarah Pendlebury, Oxford University Hospitals NHS Foundation Trust; and Professor of Medicine and Old Age Neuroscience, University of Oxford, UK Dr Peter Rothwell, Head of the Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford; and Professor of Clinical Neurology, University of Oxford, UK

The Oxford Case Histories series provides complex, case-based learning for medical trainees undertaking their exit examinations as well as consultants wishing to undertake continuing professional development. The skills necessary for confident and competent diagnosis and successful management of complex medical problems are developed through the study of individual patients. This series offers real-life cases specifically written to help enable trainees to meet the required standard prior to being awarded a certificate of completion of training (CCT). Each volume in the series is mapped to the core curricula and includes between 40-50 cases, comprising a brief clinical history and investigations, followed by questions on differential diagnosis and management, and detailed answers with discussion. At the end of each book, cases are listed by mode of presentation, aetiology, and diagnosis for quick reference. The series covers a wide range of specialties including general surgery, geriatric medicine, and infectious disease, and is an excellent revision aid for clinicians in specialist training (MRCP and above) and consultants undertaking continuing professional development. Dr Sarah Pendlebury, Oxford University Hospitals NHS Foundation Trust; and Professor of Medicine and Old Age Neuroscience, University of Oxford, UK Dr Peter Rothwell, Head of the Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford; and Professor of Clinical Neurology, University of Oxford, UK

Based around the core curriculum for specialist trainees, Oxford Case Histories in TIA and Stroke features 51 well-structured, peer-reviewed cases from the Oxford Hospitals giving detailed coverage of the specialty, including diagnostic and management dilemmas.Each case comprises a brief clinical history and the relevant examination findings; details of investigations undertaken, followed by questions on differential diagnosis and management; and detailed answers and discussion. The question-and-answer format is designed to enhance the reader''s diagnostic ability and clinical understanding.As part of the Oxford Case Histories series, this book is aimed at post-membership trainees and consultants and will be a useful resource for those preparing for exit examinations or revalidation. It will also be of interest to those who wish to improve their skills in diagnosis and management of a broad range of stroke disorders.

The Oxford Case Histories series provides complex, case-based learning for medical trainees undertaking their exit examinations as well as consultants wishing to undertake continuing professional development. The skills necessary for confident and competent diagnosis and successful management of complex medical problems are developed through the study of individual patients. This series offers real-life cases specifically written to help enable trainees to meet the required standard prior to being awarded a certificate of completion of training (CCT). Each volume in the series is mapped to the core curricula and includes between 40-50 cases, comprising a brief clinical history and investigations, followed by questions on differential diagnosis and management, and detailed answers with discussion. At the end of each book, cases are listed by mode of presentation, aetiology, and diagnosis for quick reference. The series covers a wide range of specialties including general surgery, geriatric medicine, and infectious disease, and is an excellent revision aid for clinicians in specialist training (MRCP and above) and consultants undertaking continuing professional development. Dr Sarah Pendlebury, Oxford University Hospitals NHS Foundation Trust; and Professor of Medicine and Old Age Neuroscience, University of Oxford, UK Dr Peter Rothwell, Head of the Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford; and Professor of Clinical Neurology, University of Oxford, UK

Based around the core curriculum for specialist trainees, Oxford Case Histories in TIA and Stroke features 51 well-structured, peer-reviewed cases from the Oxford Hospitals giving detailed coverage of the specialty, including diagnostic and management dilemmas.Each case comprises a brief clinical history and the relevant examination findings; details of investigations undertaken, followed by questions on differential diagnosis and management; and detailed answers and discussion. The question-and-answer format is designed to enhance the reader's diagnostic ability and clinical understanding.As part of the Oxford Case Histories series, this book is aimed at post-membership trainees and consultants and will be a useful resource for those preparing for exit examinations or revalidation. It will also be of interest to those who wish to improve their skills in diagnosis and management of a broad range of stroke disorders.

Providing a thorough overview of rapid developments in medical therapy, surgery, and angioplasty, this reference provides a complete review of carotid artery stenosis treatment, as well as a clear overview of carotid surgery and stenting. Offering chapters by seasoned authorities on epidemiology, imaging with ultrasound and angiography, cholesterol lowering, blood pressure management, homocysteine treatment, and diet modification, this guide is a stand-alone source for current information and understanding of this burgeoning science.

Providing a thorough overview of rapid developments in medical therapy, surgery, and angioplasty, this reference provides a complete review of carotid artery stenosis treatment, as well as a clear overview of carotid surgery and stenting. Offering chapters by seasoned authorities on epidemiology, imaging with ultrasound and angiography, cholesterol lowering, blood pressure management, homocysteine treatment, and diet modification, this guide is a stand-alone source for current information and understanding of this burgeoning science.

The second edition of Transient Ischemic Attack and Stroke covers the clinical background and management of the full clinical spectrum of cerebrovascular disease, from TIA to vascular dementia, in a compact, but evidence-based format making a comprehensive primer in stroke medicine. Accurate diagnosis and appropriate investigation and management have a major impact on patient outcomes in cerebrovascular disease, such as the effect of urgent antithrombotic treatment on early recurrent stroke after TIA and minor stroke, the effect of interventions such as thrombectomy and hemicraniectomy in major acute stroke, and the effect of stroke units and organised stroke care. Written by a leading team of clinicians and researchers in the field, this book will be essential to neurologists, geriatricians, stroke physicians, allied health workers and all others with an interest in stroke.

The second edition of Transient Ischemic Attack and Stroke covers the clinical background and management of the full clinical spectrum of cerebrovascular disease, from TIA to vascular dementia, in a compact, but evidence-based format making a comprehensive primer in stroke medicine. Accurate diagnosis and appropriate investigation and management have a major impact on patient outcomes in cerebrovascular disease, such as the effect of urgent antithrombotic treatment on early recurrent stroke after TIA and minor stroke, the effect of interventions such as thrombectomy and hemicraniectomy in major acute stroke, and the effect of stroke units and organised stroke care. Written by a leading team of clinicians and researchers in the field, this book will be essential to neurologists, geriatricians, stroke physicians, allied health workers and all others with an interest in stroke.

The second edition of Transient Ischemic Attack and Stroke covers the clinical background and management of the full clinical spectrum of cerebrovascular disease, from TIA to vascular dementia, in a compact, but evidence-based format making a comprehensive primer in stroke medicine. Accurate diagnosis and appropriate investigation and management have a major impact on patient outcomes in cerebrovascular disease, such as the effect of urgent antithrombotic treatment on early recurrent stroke after TIA and minor stroke, the effect of interventions such as thrombectomy and hemicraniectomy in major acute stroke, and the effect of stroke units and organised stroke care. Written by a leading team of clinicians and researchers in the field, this book will be essential to neurologists, geriatricians, stroke physicians, allied health workers and all others with an interest in stroke.