The field of solid tumor oncology is changing at an astonishing rate. To learn about new developments, generate fresh research perspectives, and then integrate these advancements into clinical practice is a daunting challenge confronting all who work in the oncology arena. The onset and rapid deployment of Internet capacities worldwide has created a mileau of global and instantaneous information access. The task of staying current is - coming even more challenging, and in some ways, more difficult to accomplish. Against this information pressure backdrop, how can yet more didactic material for the already overburdened oncology physician be justified? Based on the premise that we all must remain in a learning mode if we are to remain relevant, The University of Texas M. D. Anderson Annual of Solid Tumor Oncology is designed to focus on a single disease site in each volume. It is our belief that there is an information “gray zone” that lies - tween the peer reviewed (and increasingly electronically available) individual research - port and the large comprehensive multiauthored textbook. Between these two loci there - ists an information gap that will be best served by a succinct disease site-focused volume that provides an in-depth analysis of current multimodality care for a specific solid tumor system, as well as the areas of basic, translational, and clinical research that will emerge for future clinical application.

The MD Anderson Solid Tumor Oncology series presents the most cutting-edge surgical treatment and medical therapy for specific sites. Each year, more than 26,000 people are diagnosed with pancreatic cancer, also called a "silent" disease because it does not usually exhibit symptoms early on. This volume, Pancreatic Cancer, defines the current standard on multimodality care: surgery, chemotherapy, immunotherapy, gene therapy, radiotherapy, and a review of the latest research and clinical trials. It includes sections on:epidemiology/molecular biologyinherited pancreatic cancer syndromesstagingvarious surgical techniques and outcomesmultimodality therapyemerging and future therapiesThe individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.

The field of solid tumor oncology is changing at an astonishing rate. To learn about new developments, generate fresh research perspectives, and then integrate these advancements into clinical practice is a daunting challenge confronting all who work in the oncology arena. The onset and rapid deployment of Internet capacities worldwide has created a mileau of global and instantaneous information access. The task of staying current is - coming even more challenging, and in some ways, more difficult to accomplish. Against this information pressure backdrop, how can yet more didactic material for the already overburdened oncology physician be justified? Based on the premise that we all must remain in a learning mode if we are to remain relevant, The University of Texas M. D. Anderson Annual of Solid Tumor Oncology is designed to focus on a single disease site in each volume. It is our belief that there is an information “gray zone” that lies - tween the peer reviewed (and increasingly electronically available) individual research - port and the large comprehensive multiauthored textbook. Between these two loci there - ists an information gap that will be best served by a succinct disease site-focused volume that provides an in-depth analysis of current multimodality care for a specific solid tumor system, as well as the areas of basic, translational, and clinical research that will emerge for future clinical application.

Cancer cachexia is a complex syndrome characterized by diminished nutrient intake and progressive tissue depletion manifest clinically as anorexia and weight loss. This review examines the basic research that has addressed the fundamental derangements in host intermediary protein metabolism and evaluates current therapeutic approaches to the management of cancer cachexia. This volume provides a new approach as well as a comprehensive review of current basic and clinical research.

The field of solid tumor oncology is changing at an astonishing rate. To learn about new developments, generate fresh research perspectives, and then integrate these advancements into clinical practice is a daunting challenge confronting all who work in the oncology arena. The onset and rapid deployment of Internet capacities worldwide has created a mileau of global and instantaneous information access. The task of staying current is - coming even more challenging, and in some ways, more difficult to accomplish. Against this information pressure backdrop, how can yet more didactic material for the already overburdened oncology physician be justified? Based on the premise that we all must remain in a learning mode if we are to remain relevant, The University of Texas M. D. Anderson Annual of Solid Tumor Oncology is designed to focus on a single disease site in each volume. It is our belief that there is an information “gray zone” that lies - tween the peer reviewed (and increasingly electronically available) individual research - port and the large comprehensive multiauthored textbook. Between these two loci there - ists an information gap that will be best served by a succinct disease site-focused volume that provides an in-depth analysis of current multimodality care for a specific solid tumor system, as well as the areas of basic, translational, and clinical research that will emerge for future clinical application.

The MD Anderson Solid Tumor Oncology series presents the most cutting-edge surgical treatment and medical therapy for specific sites. Each year, more than 26,000 people are diagnosed with pancreatic cancer, also called a "silent" disease because it does not usually exhibit symptoms early on. This volume, Pancreatic Cancer, defines the current standard on multimodality care: surgery, chemotherapy, immunotherapy, gene therapy, radiotherapy, and a review of the latest research and clinical trials. It includes sections on:epidemiology/molecular biologyinherited pancreatic cancer syndromesstagingvarious surgical techniques and outcomesmultimodality therapyemerging and future therapiesThe individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.

The field of solid tumor oncology is changing at an astonishing rate. To learn about new developments, generate fresh research perspectives, and then integrate these advancements into clinical practice is a daunting challenge confronting all who work in the oncology arena. The onset and rapid deployment of Internet capacities worldwide has created a mileau of global and instantaneous information access. The task of staying current is - coming even more challenging, and in some ways, more difficult to accomplish. Against this information pressure backdrop, how can yet more didactic material for the already overburdened oncology physician be justified? Based on the premise that we all must remain in a learning mode if we are to remain relevant, The University of Texas M. D. Anderson Annual of Solid Tumor Oncology is designed to focus on a single disease site in each volume. It is our belief that there is an information “gray zone” that lies - tween the peer reviewed (and increasingly electronically available) individual research - port and the large comprehensive multiauthored textbook. Between these two loci there - ists an information gap that will be best served by a succinct disease site-focused volume that provides an in-depth analysis of current multimodality care for a specific solid tumor system, as well as the areas of basic, translational, and clinical research that will emerge for future clinical application.

Cancer cachexia is a complex syndrome characterized by diminished nutrient intake and progressive tissue depletion manifest clinically as anorexia and weight loss. This review examines the basic research that has addressed the fundamental derangements in host intermediary protein metabolism and evaluates current therapeutic approaches to the management of cancer cachexia. This volume provides a new approach as well as a comprehensive review of current basic and clinical research.