Philip N. Patsalos - Böcker

This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians, psychiatrists and general practitioners.

This essential and concise clinical reference guide serves diverse clinicians and allied health professionals who prescribe antiepileptic drugs in contemporary clinical practice. Fully updated, it features chapters on newly-approved drug brivaracetam, updated paediatric prescribing, use in particular populations including women, the elderly, and patients with cognitive impairment, as well as sections on teratogenicity, pregnancy, and lactation. In full colour throughout, the guide provides comprehensive antiepileptic drug (AED) prescribing information, covering all thirty-five AEDs in alphabetical order. Each chapter features eight coloured sections including general therapeutics, pharmacokinetics, interaction profile, adverse effects, dosing and use, special population considerations, a summary overview, and suggested reading. Perfect for quick reference use, the guide is practical and essential for all AED drug prescribers including adult and paediatric neurologists, neurosurgeons, psychiatrists, internists, geriatricians, paediatricians, family physicians, as well as allied health professionals and resident, fellow, and student trainees in all related medical fields.