R. Cooper – författare

This new book encompasses, in great detail, the most recent progress made in the isolation and separation of natural products. It covers antibiotics, marine and plant-derived substances, enzyme inhibitors and interferons. The most recent separation methodology is described. Although there is a bias toward antibiotics, it was done because this is still the largest natural products area of research.The fourteen chapters are written by experts in their respective fields. The first two chapters are largely devoted to new methodology applied to purification of a variety of compounds. They include an extensive review and new applications of counter-current chromatography and the newly emerging HPLC-photodiode array technology. Chapter 3 provides a review of affinity chromatography applied to the separation of antibiotics for the first time. Next are chapters on antimicrobials with an update on all the most recent &bgr;-lactam (after 1976) discoveries. A comprehensive review of a very important class of antiparasitic agents - the avermectins - follows. An update of isolation and purification of a variety of marine-derived compounds is next. The succeeding chapter is a comprehensive review of the most recent developments in isolation and purification of interferons. This is followed by a discussion of enzyme inhibitors and their isolation and purification and ties in with a chapter on plant-derived natural products, some of which are also in this same category. The final chapter is a futuristic essay indicating the isolation of minute amounts of natural products and the fascinating biological properties which they possess.The book has extensive isolation schemes, tables, figures and chemical structures. In many instances a short summary of the producing organism, brief chemical description and structure and biological activity of the compounds is presented. Detailed information of extraction, separation and purification techniques follow. Each chapter has an extensive bibliography and, where applicable, an appendix showing sources of materials and equipment. A detailed index to the subject matter is included at the end of the book.The book thus offers the reader: up-to-date reviews (including 1988) of specific topics in the natural products field not to be found elsewhere; information on new chromatographic methods and techniques described in sufficient detail to be utilized by investigators in this area of research; and extensive references to enable the serious researcher to pursue particular information. It will appeal to pharmaceutical and natural products researchers and is a valuable acquisition for university chemistry and biochemistry departments.

In 2005, the international community unanimously endorsed a revolutionary norm that has the potential to end genocide and other atrocity crimes in our time. Despite its endorsement at the highest political level and the general feeling of the American public that "something needs to be done" to prevent and stop atrocity crimes, the Responsibility to Protect (R2P) is very much absent from public thinking and the political agenda in the United States. Written by a stellar cast of authors, this book informs the public and leadership about R2P and its potential. It will also influence the academic, community and political debates by providing crucial insights on how to move R2P from rhetoric to action.

In 2005, the international community unanimously endorsed a revolutionary norm that has the potential to end genocide and other atrocity crimes in our time. Despite its endorsement at the highest political level and the general feeling of the American public that "something needs to be done" to prevent and stop atrocity crimes, the Responsibility to Protect (R2P) is very much absent from public thinking and the political agenda in the United States. Written by a stellar cast of authors, this book informs the public and leadership about R2P and its potential. It will also influence the academic, community and political debates by providing crucial insights on how to move R2P from rhetoric to action.

This book explores the micro-foundations and the macro-implications of the design of labour contracts.

This book explores the micro-foundations and the macro-implications of the design of labour contracts.

In the nineteenth century, the dragon Dìzhèn put the small coastal town of Everlasting under her protection. Her family was supposed to carry on the tradition, but all of Dìzhèn the Great's heirs eventually left rather than live in the shadow of such a powerful dragon, and to the people of Everlasting, the dragons are more myth than anything to rely upon.Only the youngest dragon of the current generation remains in the big house hidden among the trees: Zarrin, the softhearted disgrace of his family. He might be weak, small, and afraid, but he is determined to show the humans they have not been forgotten… and he will start with the human he has longed for since they were children. The problem is, Zarrin hasn't been around any humans much, and can barely get this one human to talk to him.A lot of the people in Everlasting think grumpy outcast Joe should love to have a dragon trying to get his attention. But Joe refuses to cower in front of the dragons or suck up to Zarrin like everyone else. Yes, Zarrin is sexy, and oddly gentle for a dragon, and stares at Joe with a gaze so hot it makes Joe shiver. But hurt, mistrustful Joe can't believe Zarrin's promises and doesn't realize he is the treasure Zarrin once let slip through his fingers. Now, to win Joe's trust, and the trust of the town, Zarrin has to learn about humans and love, so he can be as brave and strong as Dìzhèn herself.Being(s) in Love:Magical creatures known as beings emerged from hiding amid the destruction of the First World War. Since then they've lived on the margins of the human world as misunderstood objects of fear and desire. Some are beautiful, others fearsome and powerful. Yet for all their magic and strength, they are as vulnerable as anyone when it comes to matters of the heart.

For five years, Timothy Dirus has lived on the run, in fear of his family. Kept away from other werewolves by his uncle, Tim knows almost nothing about his own kind except that alpha werewolves only want to control and dominate a scrawny wolf like him. But when Tim finds himself in Wolf's Paw, one of the last surviving refuges from the days when werewolves were hunted by humans, he immediately draws the attention of its sheriff, Nathaniel Neri.Nathaniel is the epitome of alpha wolf: powerful, intimidating, and the most beautiful man Tim has ever seen. Tim should be terrified. But everything Tim feels says that Nathaniel is safe and good and right, if only Tim knew what that meant.Tim isn't sure what to trust—what he was told by his uncle, or his instincts. He's not even certain what his instincts are, and feels like a failure of a were in a town like Wolf's Paw. But Nathaniel is patient and willing to wait while his little wolf figures out not just how to be a wolf, but that he is more than a match for this particular alpha.Being(s) in Love:Magical creatures known as beings emerged from hiding amid the destruction of the First World War. Since then they've lived on the margins of the human world as misunderstood objects of fear and desire. Some are beautiful, others fearsome and powerful. Yet for all their magic and strength, they are as vulnerable as anyone when it comes to matters of the heart.

A Being(s) in Love CollectionVery little is known about seers—those individuals, both human and being, with the power to know both what could have been and what is yet to come. Seers prefer it that way. Some of them run from their visions. Others call themselves artists or authors instead of oracles. But even in the most seemingly innocent of their creations, the truth will out, and lessons will be learned.Two storytellers of different eras and vastly different temperaments weave fantastic tales of magic and romance for their enthralled audiences: A young prince avoids his betrothed and the curse that binds them. A witch uses his magic to help the man he loves court someone else. A warrior betrayed by his lord finds himself in the company of a mysterious stranger. A half-fae is doomed to be sent to the Faery Court unless he can find someone to love him. A lonely outcast finds himself drawn to a forbidden forest. A bookseller at a masked ball wonders if he should pursue a handsome prince. A dragon attempts to woo a beast. A shy servant is given one night to reach for what he wants. Fairy tales that reveal more about the tellers, and their audiences, than they might want.Being(s) in Love:Magical creatures known as beings emerged from hiding amid the destruction of the First World War. Since then they've lived on the margins of the human world as misunderstood objects of fear and desire. Some are beautiful, others fearsome and powerful. Yet for all their magic and strength, they are as vulnerable as anyone when it comes to matters of the heart.

Years ago, Martin Dyer nearly died in the woods outside Everlasting. A beautiful, inhuman creature saved his life, but Martin has done his best to forget it ever happened. He spends his time in a haze of weed as he avoids his emotionally abusive mother—and the way he feels about men. Martin is already a weirdo in his isolated small town; he doesn't need a sexuality crisis, too. He's a mess, but someone—or something—always seems to take care of him, usually a tall, sarcastic deputy by the name of Ian Forrester.No one knows much about Ian, which is how he and his family have preferred it since before Everlasting existed. Ian has resigned himself to a lonely life. He might dream of Martin, but it's only that—a dream. Martin doesn't like men, and even if he did, he doesn't like Ian. No one does, because Ian keeps his secret, and his distance, by being prickly.But the dragons and their magic have returned to Everlasting, shaking the entire town and leaving Martin questioning what he might be able to have if he sobers up and faces the truth. Now, anything seems possible, even a happily ever after for two men who never expected one.Being(s) in Love:Magical creatures known as beings emerged from hiding amid the destruction of the First World War. Since then they've lived on the margins of the human world as misunderstood objects of fear and desire. Some are beautiful, others fearsome and powerful. Yet for all their magic and strength, they are as vulnerable as anyone when it comes to matters of the heart.