R. Paoletti – författare
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5 produkter
5 produkter
881 kr
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A great deal of experimental, clinical and epidemiological data have been gathered to confirm the strict and causal correlation between plasma lipoproteins and coronary heart disease. However, as usually happens in research, many more interesting issues are being studied, opening new fields of research for the future. These new advances, together with the combined efforts of cell biologists and lipoprotein chemists, have set the pace for an exciting period of research and clinical applications of diets and drugs affecting plasma and cell lipids. This volume, which includes the work of many of the leading world labortories, represents an authoritative and up-to-date appraisal of the status of the art and a stimulus to future research at the laboratory and clinical level in a fascinating area of clinical and preventive medicine.
Del 3 - Medical Science Symposia
Calcium Antagonists
Pharmacology and Clinical Research
Inbunden, Engelska, 1993
881 kr
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Although the importance of calcium (Ca2+) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades. As the complexity of the pharmacological actions of the Ca2+ channel inhibitors grows, there is a continued need to further clarify the inhibitors, both chemically and functionally. This volume provides an update of the field based on the work presented at the 5th International Symposium on Calcium Antagonists: Pharmacology and Clinical Research. It reviews the current state of the growing area of molecular biology of Ca2+ channels in the cardiovascular area, in addition to the well-established clinical uses of Ca2+ channel inhibitors, recent work pointing to an application in atherosclerosis is described. The text also includes important uses of Ca2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.
1 209 kr
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In this work, leading physicians; hepatologists; pharmacologists; pathologists; and transplant surgeons discuss the most recent advances in the field of liver disease and its treatment. Attention is focused on epidemiology; the diagnosis of disease (clinical chemistry, histopathology, medical imaging analysis); prognosis; prediction; and clinical management. Pathogenesis of diseases such as liver cirrhosis following viral disease or alcohol abuse are discussed at length, and special attention is dedicated to high risk patients (children, fulminant hepatitis). The other major topics include terminal liver failure, for which transplantation is now routine. The latter is discussed in depth, starting from the organ donor management; organ evaluation and preservation; new surgical techniques; post-transplant patient follow-up including side effects of immunosuppression; and reports of the latest drugs used to prevent rejection.
881 kr
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This volume, based on the International Congress Creatine: From Basic Science to Clinical Application, held in Milan on June 4, 1999, outlines the physiological role of creatine in the human body as well as its possible role in different pathological conditions. Creatine is already used as a dietary supplement to augment muscle performance in healthy individuals and inpatients with immobilizing diseases, such as complex fractures. There is also an increasing interest in its administration in a growing number of clinical conditions. A specific deficit of endogenous synthesis of creatine which responds to high dosage exogenous supplementation has been described. In cardiac failure and in chronic obstructive pulmonary disease, creatine improves the contractility of the muscular system. Promising effects of this substance have also been described in animal models of neurodegenerative disorders, such as amyotrophic lateral sclerosis, and in some mitochondrial cytopathies. This volume is of obvious interest to basic scientists working on the physiology of creatine and to clinicians interested in its medical indications.
1 209 kr
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The complex relationships between alcohol use and human health represent an area of increasing interest to specialists interested in preventive cardiology. The inverse relationship between alcohol consumption and the incidence of cardiovascular diseases, especially myocardial infarction and ischemic stroke, has in fact gained sound scientific support in the last few years of the 20th century. This book, based in an international symposium on the topic held in Venice, October 30-31, 1999, analyzes in depth the epidemiological association between alcohol consumption and human diseases and discusses the possible mechanisms involved in alcohol-associated protection from atherosclerotic diseases. The oxidative effects of different amounts of alcohol intake and of various alcoholic beverages in the production of these effects - subjects of considerable debate - are also analyzed. This book should be of interest to clinicians and researchers active in the areas of atherosclerosis, public health, preventive medicine, and preventive cardiology.It is intended to specifically help practising clinicians provide their patients with evidence-based answers to the most commonly asked questions regarding alcohol use.