Ramaswamy Govindan - Böcker

Cancer Genomics for the Clinician is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. The final chapter explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more.Assembled in an accessible format specifically designed for the non-expert, this book provides the clinical oncologist, early career practitioner, and trainee with an essential understanding of the molecular and genetic basis of cancer and the clinical aspects that have led to advancements in diagnosis and treatment. With this resource, physicians and trainees will increase their breadth of knowledge and be better equipped to educate patients and families who want to know more about their genetic predispositions to cancer and the targeted therapies that could be considered and prescribed.Key Features:Describes how cancer genomics and next generation sequencing informs cancer screening, risk factors, therapeutic options, and clinical management across cancer typesExplains what mutations are, what tests are needed, and how to interpret the resultsProvides information on FDA-approved targeted therapies that are being used in the clinicCovers different sequencing platforms and technologies and how they perform in research settingsIncludes access to the fully searchable eBook

Based on DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology, Eleventh Edition, this comprehensive review book covers the entire specialty of oncology, including new or expanded coverage of molecular biology; epidemiology and etiology; screen and prevention; genetics; clinical trials; and immunotherapy. Inside, readers will discover hundreds of multiple-choice and case-based questions, along with detailed answers and explanations to help explain the how and why behind each correct response. The ideal way to maximize exam scores for today’s student and residents!Learning and review features include: Hundreds of multiple-choice and case-based questions to build comprehension and improve retention.All topics cross-referenced to the latest edition of DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology, Eleventh Edition.Material on all aspects of oncology, including medical, radiation and surgical oncology, as well as hematology/oncology issuesEnrich Your eBook Reading ExperienceRead directly on your preferred device(s),such as computer, tablet, or smartphone.Easily convert to audiobook,powering your content with natural language text-to-speech.

Focusing on the essential information you need to know for the clinical practice of oncology, this practical volume in the Lippincott Manual series provides concise, high-yield content that reflects today’s fast-changing advances in the field. In one convenient, portable resource, you’ll find complete coverage of cancer management, all at your fingertips for quick review and reference. The Washington Manual® of Oncology, 4th Edition, by Drs. Daniel Morgensztern, Armin Ghobadi, and Ramaswamy Govindan, is an ideal reference for oncologists, residents, fellows, medical students, nurse practitioners, and physician assistants. , The latest, most reliable cancer management recommendations in the famous fast-access Washington Manual® outline format that includes easy-to-follow guidelines, tables, graphs, and algorithms. Thoroughly revised from cover to cover, including new content on gene and cellular immunotherapy for cancer, management of antineoplastic-induced nausea and vomiting as well as new sections on neuroendocrine carcinoma and myelodysplastic syndromes. Concise, clearly written sections on the principles of oncology, site-specific cancers, and therapy and support. Key information on chemotherapeutic agents and regimens in the appendices.   The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by WoltersKluwer Health under license from Washington University. , Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. ,