Ramesh K. Gupta – författare

This book presents the morphological details of various opportunistic pathogens for prompt identification, which is essential for the proper management of various bacterial, viral, fungal and parasitic infections encountered in immunocompromised patients.

Over the past few decades, certain therapeutic advances –such as organ transplantation, prolonged use of steroids and other immunosuppressants for various diseases and chemo-radiotherapy for the treatment of malignant tumors– have, in addition to improving patient survival, also contributed to significant aberrations in the patients’ host defense mechanisms. Further, due to compromised host resistance, certain clinical conditions such as HIV/AIDS, diabetes mellitus, and major organ-related problems like chronic renal failure, chronic liver and chronic lung diseases etc., make these patients potentially vulnerable to a variety of opportunistic infections.

 The challenges posed by the opportunistic pathogens are enormous. Early clinical suspicion, prompt morphological identification and timely management are essential so as to prevent high morbidity and mortality associated with these infections. These pathogens often go unnoticed due to a lack of familiarity with their morphological appearances in the context of histopathological and/or cytological evaluation.

This book provides clear understanding of morphological appearances of various glomerular lesions encountered in a wide range of diseases involving renal glomeruli. Chapters cover various diseases with each chapter including a brief text and multiple colored microphotographs depicting the distinctive morphological features of glomeruli as may be encountered in these diseases. It presents complete clinical history with thorough lab workup and other related investigations as considered essential for proper evaluation of the patient. The book provides systemic approach for proper diagnosis of the underlying disease condition in view of the clinical workup and renal biopsy assessment.