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5 produkter
5 produkter
1 870 kr
Skickas inom 10-15 vardagar
In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression.Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development.
1 870 kr
Skickas inom 10-15 vardagar
In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression.Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development.
Del 76 - Stem Cell Biology and Regenerative Medicine
Cancer Stem Cells and Cancer Therapy
Inbunden, Engelska, 2025
2 418 kr
Skickas inom 10-15 vardagar
This book explores the importance of cancer stem cells and their usage. Cancer is a serious health issue that affects people all over the world. Numerous studies back up the theory that stem cells play a role in cancer development. The population of cancer stem cells (CSCs) exhibits tumorigenic potential and possesses stem cell-specific markers and characteristics, such as self-renewal/proliferation and differentiation. Carcinogenesis may be significantly influenced by CSCs. Currently, treatment techniques concentrate on eliminating the CSC subpopulation using various methods, such as bypassing CSC resistance mechanisms or focussing on important biochemical pathways that govern these cells. New approaches are still required even though the negative effects of current treatment approaches are minimal.The information that has been gathered on the stem cell theory of carcinogenesis, the impact of dysregulated stem cell self-renewal on cancer transformation, and the functions of CSCs in cancer treatment are presented in this book. We also discuss how a deeper comprehension of the biology, behaviour, and environment of CSCs can advance the use of these cells in cancer therapy and lead to the development of more potent cancer treatment plans.Given its scope, Cancer Stem Cells and Cancer Therapy is an indispensable resource not only for researchers working in the field of human biology and cancer research but also for advanced students seeking an introduction to cancer stem cells and their therapeutic usage.
Del 76 - Stem Cell Biology and Regenerative Medicine
Cancer Stem Cells and Cancer Therapy
Häftad, Engelska, 2026
2 418 kr
Skickas inom 10-15 vardagar
This book explores the importance of cancer stem cells and their usage. Cancer is a serious health issue that affects people all over the world. Numerous studies back up the theory that stem cells play a role in cancer development. The population of cancer stem cells (CSCs) exhibits tumorigenic potential and possesses stem cell-specific markers and characteristics, such as self-renewal/proliferation and differentiation. Carcinogenesis may be significantly influenced by CSCs. Currently, treatment techniques concentrate on eliminating the CSC subpopulation using various methods, such as bypassing CSC resistance mechanisms or focussing on important biochemical pathways that govern these cells. New approaches are still required even though the negative effects of current treatment approaches are minimal.The information that has been gathered on the stem cell theory of carcinogenesis, the impact of dysregulated stem cell self-renewal on cancer transformation, and the functions of CSCs in cancer treatment are presented in this book. We also discuss how a deeper comprehension of the biology, behaviour, and environment of CSCs can advance the use of these cells in cancer therapy and lead to the development of more potent cancer treatment plans.Given its scope, Cancer Stem Cells and Cancer Therapy is an indispensable resource not only for researchers working in the field of human biology and cancer research but also for advanced students seeking an introduction to cancer stem cells and their therapeutic usage.
Epigenetics in Neurodegenerative Disorders
Mechanisms, Biomarkers, and Therapeutic Perspectives
Inbunden, Engelska, 2026
2 902 kr
Kommande
Epigenetic mechanisms are increasingly recognised as key contributors to neurodegenerative disease processes, shaping the molecular pathways involved in ageing, neuroinflammation and neuronal dysfunction. This volume provides an integrated overview of how DNA methylation, histone modifications, chromatin remodelling, non‑coding RNAs and epitranscriptomic regulation influence the onset and progression of neurodegenerative disorders.Covering a broad spectrum of conditions—including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, frontotemporal dementia, prion and prion‑like diseases, amyotrophic lateral sclerosis and multiple sclerosis—the book examines how epigenetic alterations interact with genetic, metabolic and environmental factors to drive disease pathology. Contributors detail advances in biomarker development, such as DNA methylation profiles, differentially methylated and hydroxymethylated regions, extracellular vesicles and neurofilament light chain, along with emerging therapeutic strategies involving CRISPR‑based epigenetic editing, histone deacetylase inhibitors and DNA methyltransferase inhibitors.Additional chapters explore cross‑disease themes including neuroinflammatory signalling, gut–brain epigenetic interactions, chromatin dynamics and ageing‑related epigenetic drift, offering insights into translational research and precision medicine. This volume serves as a valuable resource for researchers, clinicians and advanced students in neuroscience, molecular biology, genetics and biomedical sciences seeking to understand the role of reversible epigenetic regulation in neurodegenerative disorders.