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This is an essential guide to the data, basic science, outcome studies and decision-making processes involved in blood and marrow stem cell transplantation. Organized according to disease types and procedures, it contains more than 100 tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between different types of chemotherapy, autologous vs. allogeneic transplantation, peripheral blood vs. bone marrow stem cells, and standard vs. experimental treatments. This new edition summarizes the research of the last four years and gives mature data for all established indications, such as acute myeloid leukemia, myelodysplastic syndrome and Hodgkin and non-Hodgkin lymphomas. New chapters discuss global trends in stem cell transplantation, cellular therapies including donor lymphocytes, and pediatric neurologic and metabolic disorders. With an expanded complications section, links to electronic databases and discussion of new drugs and alternative stem cell sources, this text belongs in every transplant unit.

This authoritative new book provides a comprehensive overview of diagnostic and therapeutic strategies in hematopoietic cell transplantation, explaining key concepts, successes, controversies and challenges. The authors and editors discuss current and future strategies for major challenges, such as graft-versus-host-disease, including new prophylaxis and treatments. They also discuss long-term complications, such as second malignancies and cardiovascular complications. Chapters are written by leading world experts, carefully edited to achieve a uniform and accessible writing style. Each chapter includes evidence-based explanations and state-of-the-art solutions, providing the reader with practice-changing advice. Full reference lists are also supplied to facilitate further exploration of each topic. Each copy of the printed book is packaged with a password, giving readers online access to all text and images. This inspiring resource demystifies both the basics and subtleties of hematopoietic cell transplantation, and is essential reading for both senior clinicians and trainees.

Over the past few decades the powerful methods of statistical physics and Euclidean quantum field theory have moved closer together, with common tools based on the use of path integrals.