Rexford S. Ahima - Böcker

How can we work together to understand the rise of obesity and reverse its related diseases and societal impacts?Obesity is a complex condition that increases a person's risk for developing diabetes, heart disease, cancer, dementia, and other life-threatening conditions. Contrary to prevailing notions that it results solely from a person's diet and exercise failings, a predisposition to obesity is actually determined by genetics as well as by environmental and socioeconomic factors that lie beyond individual control. In Can the Obesity Crisis Be Reversed?, Dr. Rexford Ahima draws on his extensive laboratory and clinical experiences at top institutions to examine the complicated causes of obesity, as well as the most cutting-edge approaches for prevention and treatment. Ahima looks at how the rising trends of obesity and associated diseases are driving up health care costs. He also offers insight into the widespread suffering that obesity imposes and its disproportionate impacts in minority and underserved communities.Calling for greater societal and community engagement in stemming the obesity crisis, Ahima argues that there is an urgent need to promote healthier foods and environmental infrastructure as well as formal programs that reduce obesity. By understanding and applying fundamental knowledge, Can the Obesity Crisis Be Reversed? makes a convincing case that all of us, working individually and collectively, can help to reverse the obesity crisis.Features• Provides information on the biological pathways that control eating and metabolism• Explains genetic and environmental bases of obesity• Reviews the contributions of diet and physical activity to weight gain while speaking to the folly and dangers of individual blame• Offers practical recommendations for healthy diets, exercise, and lifestyle• Discusses current medical and surgical treatments of obesity• Examines comprehensive societal strategies for obesity preventionJohns Hopkins WavelengthsIn classrooms, field stations, and laboratories in Baltimore and around the world, the Bloomberg Distinguished Professors of Johns Hopkins University are opening the boundaries of our understanding of many of the world's most complex challenges. The Johns Hopkins Wavelengths book series brings readers inside their stories, illustrating how their pioneering discoveries benefit people in their neighborhoods and across the globe in artificial intelligence, cancer research, food systems' environmental impacts, health equity, science diplomacy, and other critical arenas of study. Through these compelling narratives, their insights will spark conversations from dorm rooms to dining rooms to boardrooms.

The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.

The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.

The Year in Diabetes and Obesity will fulfill a critical need in by publishing timely, thought-provoking reviews on the molecular, basic, and clinical aspects of diabetes and obesity.  Reviews in the inaugural issue will include:  Early life nutrition and Metabolic Programming; Neuroendocrine Responses to Hypoglycemia; Cardiovascular Outcomes in Type 2 Diabetes: The Impact of Preventative Therapies; Gastrointestinal Hormones and beta-cell Mass Regulation; CNS leptin and Insulin Action in the Control of Energy Homeostasis; The Genetics of Type 2 Diabetes: What have we learned from GWAS?; Management of Hyperglycemia in Hospitalized Patients; Circadian control of metabolism; Metabolic surgery for type 2 diabetes; and Adipokines. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

This second installment of The Year in Diabetes and Obesity review series includes thought-provoking reviews on  central nervous system control of glucose and energy metabolism; stearoyl CoA desaturase in obesity and metabolism; circadian disruption and metabolic dysfunction; incretin hormones; metabolic syndrome, adipokines, and dementia; interventions for the prevention or reversal of type 1 diabetes; the role of intestinal microbiome in humans and mice with type 1 diabetes; building smarter and better insulins; RAGE––a multi-ligand receptor in chronic diseases; diabetes, cancer risk, and metformin––connections of metabolism and cell proliferation; prevalence of diabetes in Asia; and prioritization of care in adults with diabetes and co-existing chronic conditions. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

This third installment of The Year in Diabetes and Obesity review series includes reviews with a special focus on metabolic syndrome and health. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

This title includes a number of Open Access chapters.The book provides a comprehensive perspective on the subject of obesity epidemiology, pathophysiology, and management of obesity. The chapters provide a better understanding of obesity and obesity-related diseases and offer an integrative framework for individualized dietary and exercise programs, behavior modification, pharmaceutical approaches, surgery, and population interventions to reduce the growing epidemic of obesity.

This title includes a number of Open Access chapters.The prevalence of childhood overweight and obesity has increased worldwide in recent decades. Obesity in childhood is associated with a wide range of serious health complications and an increased risk of premature illness and death later in life. This book presents childhood obesity trends across multiple demographics and discusses the contributing genetic and environmental factors. It demonstrates the adverse health consequences of childhood obesity both as they relate to childhood and as they last into adulthood and presents multiple methods for obesity treatment included community and family-based intervention, pharmacotherapy, and surgical procedures.

This title includes a number of Open Access chapters.The book provides a comprehensive perspective on the subject of obesity epidemiology, pathophysiology, and management of obesity. The chapters provide a better understanding of obesity and obesity-related diseases and offer an integrative framework for individualized dietary and exercise programs, behavior modification, pharmaceutical approaches, surgery, and population interventions to reduce the growing epidemic of obesity.

This title includes a number of Open Access chapters.The prevalence of childhood overweight and obesity has increased worldwide in recent decades. Obesity in childhood is associated with a wide range of serious health complications and an increased risk of premature illness and death later in life. This book presents childhood obesity trends across multiple demographics and discusses the contributing genetic and environmental factors. It demonstrates the adverse health consequences of childhood obesity both as they relate to childhood and as they last into adulthood and presents multiple methods for obesity treatment included community and family-based intervention, pharmacotherapy, and surgical procedures.