Richard D. Chambers – författare

Leading investigators in their fields present a broad perspective of recent major research trends in synthetic fluorine chemistry. Coverage includes: various aspects of organic and inorganic fluorine chemistry, fluorination methods, organometallic fluorine chemistry and its use in synthesis, the synthesis of perfluoropolyethers (an extraordinary class of new fluorinated compounds) and much more.

The introduction of carbon – fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties.In this new book the author, internationally known for his contribution to organic fluorine chemistry, covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems. Written as an authoritative guide to the subject for organic chemists in universities and the pharmaceutical, agrochemical, specialty organic and polymer industries, the book will also be an important resource for university advanced courses. Dick Chambers is a Fellow of the Royal Society and Emeritus Professor of Chemistry at the University of Durham, Durham, UK.

Fluorine is unique in that it is possible to replace hydrogen by fluorine either singly or multiply,in an organic molecule and,in so-doing create a potentially infinite extension to organic chemistry that is entirely synthetic. The excitement of the chemistry of these systems stems from the unique reactions that ensue and the "special-effects"that introduction of fluorine impart. Indeed,these effects are now exploited in a remarkable array of applications across the whole of the chemical,pharmaceutical,and plant-protection industries,although this is not widely appreciated. In this book, we have gathered authors with immense experience in various aspects of their field and each is a world-authority on the important topics they have described. Some topics, like the use of elemental fluorine, and enzymes in synthesis, are relatively new areas that are rapidly growing. We dedicate the book to a long standing friend,Professor George Olah,in the year of his 70th birthday,in recognition of his massive achievements. Durham,May 1997 Dick Chambers Contents Elemental Fluorine in Organic Chemistry J. Hutchinson and G. Sandford ...1 Fluorinated Organometallic Compounds D. J. Burton and L. Lu ...45 Enzymatically Controlled Reactions of Organofluorine Compounds T. Kitazume and T. Yamazaki ...91 Building Block Approaches to Aliphatic Organofluorine Compounds J. M. Percy ...131 Electrofluorination of Organic Compounds F. G. Drakesmith ...197 Author Index Volumes 151-193 ...243 Contents of Volume 192 Organofluorine Chemistry: Fluorinated Alkenes and Reactive Intermediates Volume Editor: R. D. Chambers Nucleophilic Reactions of Fluorinated Alkenes R. D. Chambers and J. F. S.

The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.

The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.