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Mismatch negativity (MMN) is the electrophysiological change-detection response of the brain. MMN is stimulated when there is any discernible change to a repetitive sequence of sound, occurring even in the absence of attention. MMN is an automatic response and causes an involuntary attentional shift, representing a function which is of vital significance. A parallel response can also be detected in the other sensory modalities- visual, somatosensory, and olfactory.MMN occurs in different species, and across the different developmental stages, from infancy to old age.Importantly, the MMN response is affected in different cognitive brain disorders, providing an index to the severity of the disorder and consequently, a guide to the effectiveness of different treatments. MMN has become extremely popular around the world for investigating a wide range of clinical populations. It is a versatile tool for studying perception, memory, and learning functions in both the healthy and dysfunctional brain. Furthermore, being elicited irrespective of attention, it isideal for investigating inattentive participants, such as sleeping infants or patients in a coma, whose cognitive processes are otherwise hard to access.Written by pioneers and leading authorities in the subject, this book provides an introduction to MMN and its contribution within different clinical fields: developmental disorders, neurological disorders, psychiatric disorders, and aging.

This book is a testimony to Evgeny Nikolaevich Sokolov's years of work in developing knowledge in the areas of perception, information processing and attention, and to the research it has spawned. It presents a historical account of a research program, leading the reader toward a cognitive science approach to the study of perception and attention. An understanding of neuroscience and mathematical modeling are helpful prerequisites. The co-authors collected data on orienting, attention, and information processing in the brain using single-cell recordings, central, autonomic, cognitive, behavioral, and verbal measures. This commonality brought them together for a series of meetings which resulted in the production of this book. The book ends with a review of some of the co-authors studies that have developed from or in parallel with Sokolov's research. They investigate, in particular, the concepts of attention and anticipation using a psychophysiological methodology.

This book is a testimony to Evgeny Nikolaevich Sokolov's years of work in developing knowledge in the areas of perception, information processing and attention, and to the research it has spawned. It presents a historical account of a research program, leading the reader toward a cognitive science approach to the study of perception and attention. An understanding of neuroscience and mathematical modeling are helpful prerequisites. The co-authors collected data on orienting, attention, and information processing in the brain using single-cell recordings, central, autonomic, cognitive, behavioral, and verbal measures. This commonality brought them together for a series of meetings which resulted in the production of this book. The book ends with a review of some of the co-authors studies that have developed from or in parallel with Sokolov's research. They investigate, in particular, the concepts of attention and anticipation using a psychophysiological methodology.