Robert C. Elston - Böcker

Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures.This Book: Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares.Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research.Is illustrated throughout with simple examples to clarify the statistical methodology.Explains Bayes’ theorem pictorially.Features exercises, with answers to alternate questions, enabling use as a course text.Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures.This Book: Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares.Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research.Is illustrated throughout with simple examples to clarify the statistical methodology.Explains Bayes’ theorem pictorially.Features exercises, with answers to alternate questions, enabling use as a course text.Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology. This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference.

Analysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology.

Analysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in Analysis of Genetic Association Studies particularly relevant.  The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology.   In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications.  Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge.  The organization of this work allows for both casual reference and close study.

Recent advances in genetics over the last quarter of a century, especially in molecular techniques, have dramatically reduced the cost of determining genetic markers and hence opened up a field of research that is increasingly helping to detect, prevent and/or cure many diseases that afflict humans.

The aim of this volume is to make computer programs for analyzing human genetic data more easily accessible to the beginner.Statistical Human Genetics: Methods and Protocols, Second Edition provides updated and new chapters detailing genetic terms, analysis software, and how to interpret the program outputs. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, step-by-step instructions, and tips on troubleshooting and avoiding known pitfalls.  The purpose of Statistical Human Genetics: Methods and Protocols, Second Edition is to ensure successful and meaningful results in the fast-growing field of genetic epidemiology.

The aim of this volume is to make computer programs for analyzing human genetic data more easily accessible to the beginner.Statistical Human Genetics: Methods and Protocols, Second Edition provides updated and new chapters detailing genetic terms, analysis software, and how to interpret the program outputs.