Robert G. Webster – författare

Are infectious diseases caused by novel entities, viruses that have rapidly evolved into more pathogenic forms, or viruses that have crossed species divides and become more virulent in their alternative host? These questions and how new diseases such as AIDS emerged have prompted renewed interest in the ways viruses originated and co-evolved with their hosts.Origin and Evolution of Viruses presents a full and clear description of general viral concepts and specific viral systems, and provides an excellent foundation to our understanding of how viruses emerged.This unique and comprehensive work is essential reading for all researchers in virology, molecular biology and related areas, as well as evolutionary biologists interested in phylogenetic approaches to molecular evolution. The reader is taken on an illumination journey--in time and concepts--from the first primitive replicons to their present-day complex viral counterparts. Apart from the obvious interest, as humans are potential hosts for these viruses, there is also a great deal of academic interest in the evolutionary aspects of this simple group of organisms, since information can be gained about the origin of stains/species and evolutionary patterns that might be applicable to higher species.The book addresses:* Nature and evolution of early replicons* DNA and RNA viruses in both plants and animals* Viral origin, mutation, and survival* Antigenic variation in influenza virus* Interplay between host evolution and DNA virus evolution* Emergence of viral-induced diseases, e.g. hepatitis, influenza and HIV

In recent years, progress in the field of virology has advanced at an unprecedented rate. Issues such as AIDS have brought the subject firmly into the public domain and its study is no longer confined solely to specialist groups.The Encyclopedia of Virology is the largest single reference source of current virological knowledge. It is also the first to bring together all aspects of the subject for a wide variety of readers. Unique in its use of concise ''mini-review'' articles, the material covers biological, molecular, and medical topics concerning viruses in animals, plants, bacteria, and insects.More general articles focus on the effects of viruses on the immune system, the role of viruses in disease, oncology, gene therapy, and evolution, plus a wide range of related topics.Drawing on the latest research, the editors have produced the definitive source for both specialist and general readers. Easy-to-use and meticulously organized, the Encyclopedia of Virology clarifies and illuminates one of the most complex areas of contemporary study. It will prove an invaluable addition to libraries, universities, medical and nursing schools, and research institutions around the world.The Second Edition has been thoroughly updated with approximately 40 new articles. This edition includes more illustrations and color plates in each volume.- Updated thoroughly with approximately 40 new articles- Presents more illustrations than the first edition, with color plates in each volume- Contains a complete subject index in each volume- Provides further reading lists at the end of each entry, allowing easy access to the primary literature- Extensive cross-referencing system links all related articles- Contains the most recent information of particular viruses described at the 7th International Committee on Taxonomy and Classification of Viruses- Provides the ability to search for entries alphabetically or via the taxonomical listings to access articles of different viruses

The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health.Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain.This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering:• Influenza Perspectives• Structure and Replication• Evolution and Ecology• Epidemiology and Surveillance• Immunology• Vaccines and Vaccine Development• Clinical Aspects and Antivirals• Public HealthTextbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.

The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health.

Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain.

This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: • Influenza Perspectives • Structure and Replication • Evolution and Ecology • Epidemiology and Surveillance • Immunology • Vaccines and Vaccine Development • Clinical Aspects and Antivirals • Public Health

Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.