Rodrigo Hasbun – författare

Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease.Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.

Reviews the role and function of specialized Blood-Neuronal BarriersCovers various forms of brain infections, encephalitis, and meningitisFeatures content on SARS-Cov-2 and CNS, including pathogenesis to clinical manifestation

Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease.Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.- Reviews the role and function of specialized Blood-Neuronal Barriers- Covers various forms of brain infections, encephalitis, and meningitis- Features content on SARS-Cov-2 and CNS, including pathogenesis to clinical manifestation

The award-winning and haunting novel from Rodrigo Hasbún, the literary star Jonathan Safran Foer calls, “a great writer,” about an unusual family’s breakdown—set in South America during the time of Che Guevara and inspired by the life of Third Reich cinematographer Hans Ertl.Inspired by real events, Affections is the story of the eccentric, fascinating Ertl clan, headed by the egocentric and extraordinary Hans, once the cameraman for the Nazi propagandist Leni Riefenstahl. Shortly after the end of World War II, Hans and his family flee to Bolivia to start over. There, the ever-restless Hans decides to embark on an expedition in search of the fabled lost Inca city of Paitití, enlisting two of his daughters to join him on his outlandish quest into the depths of the Amazon, with disastrous consequences. “A one-sitting tale of fragmented relationships with a broad scope, delivered with grace and power” (Kirkus Reviews, starred review), Affections traces the Ertls’s slow and inevitable breakdown through the various erratic trajectories of each family member: Hans’s undertakings of colossal, foolhardy projects and his subsequent spectacular failures; his daughter Monika, heir to his adventurous spirit, who joins the Bolivian Marxist guerrillas and becomes known as “Che Guevara’s avenger”; and his wife and two younger sisters left to pick up the pieces in their wake. “Hasbún writes with patience and precision, revealing the family’s most intimate thoughts and interactions: first smokes, blind love, and familial devotion. This is a novel to savor for its richness and grace and its historical and political scope” (Booklist, starred review)—a masterfully layered tale of how a family’s voyage of discovery ends up eroding the affections that once held it together.

“It’s impossible to get a single answer from the past. It’s not a key to anything. It’s just a place we go to trick ourselves.”Andrea and Julián haven’t seen one another in twenty-one years—not since the tragic, fateful night their senior year of high school that marked their group of friends forever. A startling phone call brings the two together again in Houston, where they begin to unravel the truth of that year, picking open long scabbed-over wounds from their upper-class adolescence in 1990s Bolivia and the scandal that ripped them apart.A writer unhappy in his career and his marriage, Julián has been novelizing the past for his next book, trying to make meaning out of the events that changed the course of their lives forever. “I’d thought that writing about that time would free me, relieve the burden of the invisible years,” he writes, “but often it seems that it’s done the reverse.” Juxtaposing the naïve invincibility of adolescence with the grasping uncertainties of adulthood, The Invisible Years deftly weaves a coming-of-age tale that leaves the reader hanging on every word, even as they know how the cards fall in the end.

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae.  The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs,  overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases.  Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed.This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, includinghealthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients.Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae.  The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs,  overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases.  Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed.This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, includinghealthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients.Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae.  The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs,  overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases.  Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed.This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, includinghealthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients.Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.