The third edition of this definitive and highly-regarded reference work provides a comprehensive review of vasculitis, a fascinating array of life-threatening and minor conditions caused by inflammatory syndromes and diseases that affect the blood vessels. The text uniquely brings together concepts from both the biological and clinical aspects of vasculitis. Research in clinical immunology now invigorates the entire area of vasculitis and shapes a rational approachto pathogenesis, diagnosis, and treatment, which is the substance of this text. Over 40 chapters cover known vasculitic conditions, and are illustrated with over 250 full-colour photographs of clinical and pathologic findings, diagrams, and tables. Separate sections are devoted to basic science,clinical manifestations commonly seen in vasculitis, imaging and percutaneous interventions, individual diseases and syndromes, as well as conditions which can mimic vasculitis. Many of the conditions are rare, and it is the exceptional clinician who has much experience with more than a few of these; thus, the invaluable experience of the international team of authors makes this edition truly indispensible.Now in the Oxford Textbooks in Rheumatology series, this new edition of Vasculitis is published with a concurrent online version, which features access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint.This volume is the definitive reference for rheumatologists, clinical immunologists, and general internists, and will also be of interest to dermatologists, gastroenterologists, cardiologists, pulmonologists, nephrologists, neurologists, pathologists, vascular surgeons, and pediatricians.

This issue of Rheumatic Disease Clinics focuses on Genetics. Article topics cover: Genetic Influences on Susceptibility and Severity of Rheumatoid Arthritis; HLA-disease associations in rheumatoid arthritis; Autoinflammatory Syndromes as a Model of Monogenic Diseases; Genomic Influences on Hyperuricaemia and Gout; Genetics of Systemic Lupus Erythematosus; Genetics of Ankylosing Spondylitis;Genetics of Scleroderma; Genetics of Osteoarthritis; Genetics of Juvenile Inflammatory Arthritis; Genetic Influences on Treatment Response in Rheumatic Diseases; Integrative approaches/computational biology; Future directions of genetic research in rheumatic diseases; and Population genetics and natural selection in rheumatic disease.

The third edition of this definitive and highly-regarded reference work provides a comprehensive review of vasculitis, a fascinating array of life-threatening and minor conditions caused by inflammatory syndromes and diseases that affect the blood vessels. The text uniquely brings together concepts from both the biological and clinical aspects of vasculitis. Research in clinical immunology now invigorates the entire area of vasculitis and shapes a rational approachto pathogenesis, diagnosis, and treatment, which is the substance of this text. Over 40 chapters cover known vasculitic conditions, and are illustrated with over 250 full-colour photographs of clinical and pathologic findings, diagrams, and tables. Separate sections are devoted to basic science,clinical manifestations commonly seen in vasculitis, imaging and percutaneous interventions, individual diseases and syndromes, as well as conditions which can mimic vasculitis. Many of the conditions are rare, and it is the exceptional clinician who has much experience with more than a few of these; thus, the invaluable experience of the international team of authors makes this edition truly indispensible.Now in the Oxford Textbooks in Rheumatology series, this new edition of Vasculitis is published with a concurrent online version, which features access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint.This volume is the definitive reference for rheumatologists, clinical immunologists, and general internists, and will also be of interest to dermatologists, gastroenterologists, cardiologists, pulmonologists, nephrologists, neurologists, pathologists, vascular surgeons, and pediatricians.

This issue of Rheumatic Disease Clinics focuses on Genetics. Article topics cover: Genetic Influences on Susceptibility and Severity of Rheumatoid Arthritis; HLA-disease associations in rheumatoid arthritis; Autoinflammatory Syndromes as a Model of Monogenic Diseases; Genomic Influences on Hyperuricaemia and Gout; Genetics of Systemic Lupus Erythematosus; Genetics of Ankylosing Spondylitis;Genetics of Scleroderma; Genetics of Osteoarthritis; Genetics of Juvenile Inflammatory Arthritis; Genetic Influences on Treatment Response in Rheumatic Diseases; Integrative approaches/computational biology; Future directions of genetic research in rheumatic diseases; and Population genetics and natural selection in rheumatic disease.