This volume critically examines current methods for detecting and identifying mutagens in the environment. It describes the molecular mechanisms of mutagenesis, and assesses the involvement of mutagens in cancer and inherited disease. Full details are provided on all the major in vivo and in vitro methods of mutagenicity testing, including fluorescence in situ hybridization, the use of genetically engineered cells, and transgene technology.

This volume critically examines current methods for detecting and identifying mutagens in the environment. It describes the molecular mechanisms of mutagenesis, and assesses the involvement of mutagens in cancer and inherited disease. Full details are provided on all the major in vivo and in vitro methods of mutagenicity testing, including fluorescence in situ hybridization, the use of genetically engineered cells, and transgene technology.