Sanjay Kalra – författare

Incretins are a group of gastrointestinal hormones that cause an increase in the amount of insulin released from cells in the pancreas after eating. Incretin based drugs are used to control blood sugar levels in the management of diabetes.This book is a concise guide to incretin based therapy. Beginning with an introduction to the history and physiology of incretins, the following sections examine the clinical pharmacology of GLP-1 Analogues and DPP-4 Inhibitors, the pleiotrophic effects of incretins and comparative pharmacology.Each section integrates science with practical therapeutic guidance for clinicians involved in the management of diabetes. The final chapter discusses the future of incretin therapies, including non-diabetic usage and combination therapy.Key FeaturesConcise overview of incretin based therapy for the management of diabetesGuides clinicians step by step through the history and pharmacology of various moleculesIntegrates science with practical therapeutic guidanceIncludes chapter on the future of incretin therapy

This book is a guide to the diagnosis and management of diabetes in children.Beginning with an overview of the disease and the effect of Type 1 diabetes on the growth and development of children, the next chapter explains clinical examination and laboratory investigations.The following sections provide in depth discussion on pharmacological and non-pharmacological managements techniques, and acute and chronic complications.The book concludes with the treatment of diabetes in special cases such as in neonates and infants, and a final section cover miscellaneous topics including genetics of Type 1 diabetes, and educational material for patients and their parents.This comprehensive text has been written in association with the Changing Diabetes® in Children (CDiC) program, providing care and life-saving medication for children with Type 1 diabetes in low and middle-income countries.Key pointsComprehensive guide to the diagnosis and management of diabetes in childrenCovers both pharmacological and non-pharmacological treatment methodsIncludes discussion on special cases such as diabetes in neonates and infantsWritten in association with the CDiC program

Lipocrinology describes the relationship between lipid metabolism and endocrine function in health and disease and adds a new dimension to the fields of both lipidology and endocrinology.Section 1 explores the impact of endocrine function on lipid health and the clinical utility of lipid parameters in decision-making in endocrine disorders.Section 2 discusses the impact of adipose tissue and lipid metabolism on endocrine health, and the endocrine aspects of lipidology.Section 3 focuses on the lipotropic effects of hormone-based therapies in various endocrine disorders including diabetes and describes the endocrine effects of lipid-lowering drugs, including recently introduced PCSK-9 inhibitors.Written by experts in the field with wide clinical and research experience, this book is presented in an easy-to-read format and is a must-read book for endocrinologists, lipidologists, cardiologists, internists, clinicians, and postgraduate students.

Provides a view of the complicated interaction of glucose metabolism with various endocrine hormones. This book covers various endocrinopathies which may cause secondary diabetes or are associated with metabolic syndrome and complications/comorbidities of diabetes that may delay the diagnosis of endocrine dysfunction. It also looks at different endocrinotropic drugs that may be used to manage diabetes or may be involved in worsening of diabetes.Written by experts in the field with wide clinical and research experience.Presented in an easy to read format.A valuable resource for endocrinologists, diabetologists, clinicians and postgraduate students.

Insulin is a protein hormone that is used as a medication to treat high blood glucose. This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes.This book is a concise guide to the basics and clinical pharmacology of insulin, and the practical aspects of its use.Beginning with an overview of the development of insulins and normal physiology and metabolism, the next section examines different types of insulin (rapid-acting, short-acting, intermediate-acting, long-acting, and mixed).The following sections cover insulin therapy in type 1 diabetes, type 2 diabetes and in specific population groups. The book concludes with discussion on practical aspects of insulin therapy.Authored primarily for postgraduate medical students, the practical text is further enhanced by clinical images and diagrams to assist learning.Key pointsConcise guide to the prescription and use of insulin therapy for postgraduate studentsExplains different types of insulin and their specific usesCovers type 1 and type 2 diabetes mellitus, and specific population groupsClinical images and diagrams further enhance learning

This book covers pharmacological activity and the role of the medications used for the medical management of obesity. The chapters provide information on the prevalence of obesity, basic principles of obesity management, a brief history of anti-obesity medications (AOMs), and discontinuation of AOMs due to their safety concerns. Further chapters include information on currently approved AOMs for obesity management by healthcare regulatory authorities including their effect on weight loss and other important clinical parameters, short-term and long-term use of AOMs, medications for genetic obesity, and the use of AOMs in obesity with associated co-morbidities as per their safety considerations and contraindications. A separate chapter is on drugs that are either under a clinical trial phase or awaiting approval.The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the external editor. The editor of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that the auto-summaries consist of original sentences, but are not representative of the original paper, since we do not show the full length of the publication. Please note that only published SN content is represented here and that machine-generated books are still at an experimental stageThe book is relevant for healthcare and pharmaceutical professionals.