Sasadhar Majhi – författare

Semisynthesis of Bioactive Compounds and their Biological Activities explores the potential benefits of semisynthetic derivatives obtained from nature. Sections cover the natural distribution of parent compounds, semisynthesis and biological properties of semisynthetic derivatives, the applications of semisynthetic derivatives in diverse fields such as drug delivery, food production and medicine, an explanation of the current resistance mechanisms of antibiotics, clinical applications of semisynthetic analogues, the functions of plant alkaloids on human health, potential agricultural biotechnology in semisynthetic derivatives, and semisynthesis of natural products under greener conditions, this book provides a comprehensive resource on the topics presented.

Sections include information about alternative sources of energy and superior greener technologies (microwave, sonochemistry), alternative reaction media (water, supercritical CO2, ionic liquids) and alternative eco-friendly catalysts (biocatalysts). This book will be an excellent resource for academicians, researchers and students focusing on synthesis as well as the biological community and industry professionals in drug development.

Focuses on the current resistance mechanisms of antibiotics, chemical derivatization of antibiotics, and clinical applications of semisynthetic derivatives.Includes discussion of the semisynthesis of natural products using green tools, green solvents, and eco-friendly catalysts.Illustrates the concept of toxicity, the merits of transition-metal-free reactions, and the semisynthesis of natural products by introducing the oxygen atom(s) under transition-metal-free conditions.

Sonochemical Synthesis of Natural Products and Heterocycles of Pharmaceutical Importance: Strategy Towards a Sustainable Society comprehensively summarizes sonochemistry and ultrasound and their applicability to synthetic organic chemistry. Chapters demonstrate the application of sonochemistry to synthesizing molecules of natural origin, organic compounds containing N-heterocycles, O-heterocycles, and S-heterocycles, and the total synthesis and semisynthesis of bioactive compounds under ultrasonication through case studies and detailed illustrations and methodologies. Other sections explore sonochemical organic synthesis under solvent- and catalyst-free conditions, and in an aqueous medium as a green solvent, use of nanoparticles as efficient catalysts, and much more. This is a valuable resource for organic synthesis experts, specialists in natural products, advocates for sustainable chemistry, and researchers and professionals working in total synthesis, semisynthesis, organic synthesis, medicinal chemistry, and the pharmaceutical industries.Provides a comprehensive introduction to sonochemistry and its application to synthetic organic chemistryDemonstrates, through case studies, how ultrasound is used for developing efficient and sustainable methodologies for the synthesis of natural products and heterocyclesExplores the use of sonochemistry and ultrasound in a variety of fields, including green chemistry and pharmaceutical chemistry