Satinder Ahuja - Böcker

High pressure liquid chromatography-frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Isoelectric focusing (IEF) is a high-resolution, stand-alone technique that can be used as an analytical method or tool for protein purification. The only current book on the market, the Handbook of Isoelectric Focusing and Proteomics is the ideal 'one-stop' source for germane information in this discipline. This highly practical book also contains chapters on alternative methods that may pave the way in the search for efficient techniques for fractionating and purifying proteins. Complete with the history of IEF focusing to authors' insights and practical tips, this book is a must for anyone working in proteomics.* Is the only current book available on the subject * Includes author insights and practical tips* Is an ideal single source for students and researchers working in proteomics

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.

HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.

Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

This work provides those involved in water purification research and administration with a comprehensive resource of methods for analyzing water to assure its safety from contaminants, both natural and human caused. The book first provides an overview of major water-related issues in developing and developed countries, followed by a review of issues of sampling for water analysis, regulatory considerations and forensics in water quality and purity investigations. The subsequent chapters cover microbial as well chemical contaminations from inorganic compounds, radionuclides, volatile and semi-volatile compounds, disinfectants, herbicides, and pharmaceuticals, including endocrine disruptors, as well as potential terrorist-related contamination. The last chapter describes the Grainger prize-winning filter that can remove arsenic from water sources and sufficiently protect the health of a large number of people. Covers the scope of water contamination problems on a worldwide scale Provides a rich source of methods for analyzing water to assure its safety from natural and deliberate contaminants Describes the filter that won the $1 million Grainger prize and thereby highlighting an important approach to remediation

Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS

Many hydrological, geochemical, and biological processes associated with water reclamation and reuse are poorly understood. In particular, the occurrence and effects of trace organic and inorganic contaminants commonly found in reclaimed water necessitates careful analysis and treatment prior to safe reuse. Water Reclamation and Sustainability is a practical guide to the latest water reclamation, recycling, and reuse theory and practice. From water quality criteria and regulations to advanced techniques and implementation issues, this book offers scientists a toolkit for developing safe and successful reuse strategies. With a focus on specific contaminant removal techniques, this book comprehensively covers the full range of potential inorganic/organic contaminating compounds and highlights proven remediation methods. Socioeconomic implications related to current and future water shortages are also addressed, underscoring the many positive benefits of sustainable water resource management.

Offers pragmatic solutions to global water shortages Provides an overview of the latest analytical techniques for water monitoring Reviews current remediation efforts Covers innovative technologies for green, gray, brown and black water reclamation and reuse

How will chemists of the future balance competing concerns of environmental stewardship and innovative, cost-effective product development? For chemists to accept the idea that environmental quality and economic prosperity can be intertwined, the concept of the food-energy-water nexus must first be integrated into underlying thought processes. Food, Energy and Water: The Chemistry Connection provides today's scientists with the background information necessary to fully understand the inextricable link between food, energy and water and how this conceptual framework should form the basis for all contemporary research and development in chemistry in particular, and the sciences in general.

Presents a clear, quantitative explanation of the link between food, energy, and water Provides information not currently available in chemistry curricula or synthesized in existing resources Examines the challenges of the food-energy-water nexus from a chemistry perspective within a multi-disciplinary domain Includes the latest research on critical topics such as fracking, water use conflicts, and sustainability in food production cycles

After air, water is the most crucial resource for human survival. To achieve water sustainability, we will have to deal with its scarcity and quality, and find ways to reclaim it from various sources. Chemistry and Water: The Science Behind Sustaining the World's Most Crucial Resource applies contemporary and sophisticated separation science and chromatographic methods to address the pressing worldwide concerns of potable water for drinking and safe water for irrigation to raise food for communities around the world.

Edited and authored by world-leading analytical chemists, the book presents the latest research and solutions on topics including water quality and pollution, water treatment technologies and practices, watershed management, water quality and food production, challenges to achieving sustainable water supplies, water reclamation techniques, and wastewater reuse.

Explores the role water plays to assure our survival and maintain life Provides valuable information from world leaders in chemistry and water research Addresses water challenges and solutions globally to ensure sustainability

Ion Chromatography: Instrumentation, Techniques and Applications, Volume 13 in the series Separation Science and Technology, provides a modern overview of all aspects of ion chromatography instrumentation and chemistry techniques, including the historical backdrop of some of the key developments. Most existing books on ion chromatography are focused on single column ion chromatography (rarely used today) or applications, or are outdated. This book covers the broad range of technologies in use and explains the advantages of each, helping both experienced and new practitioners to choose the method they need.

The editors of this book have all played a key role in the success of ion chromatography at Dionex Corporation, the undisputed leader in ion chromatography for more than 40 years, and are in a unique position to describe both the technology and its applications. Ion chromatography is the technique of choice for analyzing ionic or ionizable compounds in various industries, such as pharmaceuticals and food. In addition, it is very useful for monitoring cationic or anionic impurities in drinking water.

Covers the broad range of technologies currently used in ion chromatography, with an explanation of not only how the technology works, but also which commonly used approaches represent the best options Provides a solid introduction for new practitioners to improve background knowledge on troubleshooting skills Serves as a comprehensive overview of all approaches in ion chromatography, describing the advantages of various newer technology options over older methodologies still in wide use

Advances in Water Purification Techniques: Meeting the Needs of Developed and Developing Countries provides a variety of approaches to water purification that can help assist readers with their research and applications. Water contamination problems occur frequently worldwide, hence the most updated knowledge on water purification systems can be helpful in employing the right type of filter or other mechanism of decontamination. The problems with arsenic contamination of water in Bangladesh and the lead problem in Flint, Michigan remind us of the need to monitor water pollution rigorously, from both point and non-point sources.

Provides a valuable resource on how to solve water contamination problems or develop new approaches to water purification Presents advanced methods for monitoring water contamination Describes various approaches to water purification Encourages new developments in water purification techniques Includes methods for assessing and monitoring environmental contaminants Covers recent advancement in molecular techniques

Evaluating Water Quality to Prevent Future Disasters, volume 11 in the Separation Science and Technology series, covers various separation methods that can be used to avoid water catastrophes arising from climate change, arsenic, lead, algal bloom, fracking, microplastics, flooding, glyphosphates, triazines, GenX, and oil contamination. This book provides a valuable resource that will help the reader solve their potential water contamination problems and help them develop their own new approaches to monitor water contamination.

Highlights reasons for potential water catastrophes Provides separation methods for monitoring water contamination Encourages development of new methods for monitoring water contamination

Handbook of Water Purity and Quality, Second Edition provides those involved in water purification research and administration with a comprehensive resource of methods for analyzing water to assure its safety from contaminants, both natural and human caused. The book includes an overview of the subject and discusses major water-related issues in developing and developed countries. Issues covered include sampling for water analysis, regulatory considerations, and forensics in water quality and purity investigations. Microbial as well as chemical contaminations from inorganic compounds, radionuclides, disinfectants, pesticides, and pharmaceuticals, including endocrine disruptors, are discussed at length.

In addition, the luxury of municipal water purified for human consumption is unavailable for a very large number of people. To help solve this problem, some economical water purification techniques, including a million-dollar Grainger prizewinner that can save millions of lives have been included. This fully updated second edition includes four new chapters on topics such as the GenX Water Contamination Problem, the impact of climate change on water, and green chemistry solutions to water pollution.

Covers the scope of water contamination problems on a worldwide scale with an overview of major water-related issues in developing and developed countries, including monitoring techniques for potential terrorist-related activities Provides a rich source of methods for analyzing water to ensure its safety from natural and deliberate contaminants Includes a review of water quality forensics with the objective of tracking new potential water contaminants

Separations of Water Pollutants with Nanotechnology, the latest volume in the Separation Science and Technology series, offers new solutions for remediating water pollution utilizing nanomaterials with separation methods. Current water purification methods are unsuitable, inconvenient or expensive, so there is a need for new and better processes and techniques. Nanomaterials can purify water by removing pollutants such as heavy metals, pathogens, organic compounds, inorganic compounds, pharmaceuticals, and chemicals of emerging concern. These can effectively replace membrane-based methods if the right expertise is developed-this book helps separation scientists do just that. Existing water treatment problems can be solved by applying a nanotechnology-based processes: antimicrobial nanotechnology, zero-valent iron nanoparticles, nanoadsorbents, nano-enhanced membranes, nanometal oxides, and nano photocatalysts. The current literature places emphasis on materials chemistry rather than the separation methods used for water purification. This new volume presents a collection of chapters that deal with remediation based on separation chemistry. Written by leaders in their respective fields from around the world and edited by Satinder Ahuja, a leading expert on water quality improvement Covers the environmental impact of anthropogenic nanoparticles and plant derived bionanomaterials, which are not contained in other books related to nanomaterials for water purification Illustrates key information visually wherever possible throughout the book, e.g. process diagrams in the nanomaterial synthesis and nanomembrane fabrication chapters, electron microscope images, and more

Modern Instrumental Analysis covers the fundamentals of instrumentation and provides a thorough review of the applications of this technique in the laboratory. It will serve as an educational tool as well as a first reference book for the practicing instrumental analyst. The text covers five major sections:1. Overview, Sampling, Evaluation of Physical Properties, and Thermal Analysis2. Spectroscopic Methods 3. Chromatographic Methods 4. Electrophoretic and Electrochemical Methods 5. Combination Methods, Unique Detectors, and Problem Solving Each section has a group of chapters covering important aspects of the titled subject, and each chapter includes applications that illustrate the use of the methods. The chapters also include an appropriate set of review questions.* Covers the fundamentals of instrumentation as well as key applications * Each chapter includes review questions that reinforce concepts * Serves as a quick reference and comprehensive guidebook for practitioners and students alike

Monitoring Water Quality is a practical assessment of one of the most pressing growth and sustainability issues in the developed and developing worlds: water quality. Over the last 10 years, improved laboratory techniques have led to the discovery of microbial and viral contaminants, pharmaceuticals, and endocrine disruptors in our fresh water supplies that were not monitored previously.

This book offers in-depth coverage of water quality issues (natural and human-related), monitoring of contaminants, and remediation of water contamination. In particular, readers will learn about arsenic removal techniques, real-time monitoring, and risk assessment. Monitoring Water Quality is a vital text for students and professionals in environmental science, civil engineering, chemistry - anyone concerned with issues of water analysis and sustainability assessment.

Covers in depth the scope of sustainable water problems on a worldwide scale Provides a rich source of sophisticated methods for analyzing water to assure its safety Describes the monitoring of contaminants, including pharmaceutical and endocrine disruptors Helps to quickly identify the sources and fates of contaminants and sources of pollutants and their loading

Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development.Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.

High Performance Liquid Chromatography in Biotechnology Edited By William S. Hancock Analytical chemists, biochemists, or chemical engineers will find this up-to-date guide to HPLC's recent developments essential to enhancing their on-the-job technical expertise. Extensive coverage includes the broad applications of HPLC, ranging from major chromatographic techniques (including reversed phase, ion exchange, affinity and hydrophobic interaction chromatography) to specific separations such as in monoclonal antibody and nucleic acid purification. The book also highlights the techniques required for a quality control program and such advanced technology as mass spectrometry. 1990 (0 471-82584-0) 576 pp. Unified Separation Science J. Calvin Giddings This advanced text/monograph brings together, for the first time in a single volume, the variety of techniques used for chemical separations by outlining their common underlying mechanisms. The mass transport phenomena underlying all separation processes are developed in a simple physicalmathematical form, facilitating analysis of alternative separation techniques and the factors integral to separation power. The first six chapters provide generic background material applicable to a wide range of separation methods, including the theoretical foundations of separations rooted in transport, flow, and equilibrium phenomena. The final five chapters illustrate specific techniques and methods, including electrophoretic and sedimentation techniques, field-flow fractionation, and chromatography. 1991 (0 471-52089-6) 352 pp.

High Performance Liquid Chromatography Edited by Phyllis Brown and Richard Hartwick This contributed volume is designed to consolidate the basic theories of chromatography along with the more exciting developments in the field. This monograph addresses some questions that concern researchers in separation science, including: what is the current state of the art in liquid chromatography; has the development of liquid chromatography plateaued; if so, what new methods will take its place or complement it; and if not, where will the new frontiers be and what direction will liquid chromatography take? 1989 (0 471-84506-X) 688 pp. Quantitative Structure-Chromatographic Retention Relationships R. Kaliszan Written by a pioneer in the field, this book extends and updates research on quantitative structure retention relationships by consolidating and critically reviewing the extensive literature on the subject, while also providing the basic theoretical and practical information required in all investigations involving chromatography, analytical chemistry, biochemistry, and pharmaceutical research. Among the topics covered are the nature of chromatographic interactions, molecular interpretation of distribution processes in chromatography, topological indices as retention descriptors, and multiparameter structure-chromatographic retention relationships. 1987 (0 471-85983-4) 303 pp. Detectors for Liquid Chromatography Edited by Edward S. Yeung With its singular coverage of this fast-growing field, Detectors for Liquid Chromatography presents the state of the art in this subject area. It offers a comprehensive examination of the basic principles behind the detector response, instrumentation, and selected applications for comparison and evaluation of potential. Specifically, topics given in-depth coverage include polarimetric, indirect absorbance, refractive index detectors, absorption detectors for HPLC, FTIR and fluorometric detection, detection based on electrical and electromechanical measurements, and mass spectroscopy as an on-line detector for HPLC. 1986 (0 471-82169-1) 366 pp.

For more than a century, national and international governing bodies have had some involvement in regulating the quality and safety of food during production and delivery. Since the beginnings of this "modern" food regulation in the early 20th century, the way that food is produced, packaged and distributed has changed drastically. It is difficult to determine if technological advances in the areas of polymer science, refrigeration, and transportation have driven theglobalization of the food supply or if the food industry has drawn from these technologies to satisfy consumer's desire and need.Ensuring the safety of food requires a complex and ever-changing set of interactions between producers, distributors, consumers and regulators. As advances are made in packaging and food additives, as food distributions systems evolve to meet consumer needs, or as these respond to environmental and population changes, adjustments to regulatory systems may become necessary. Analytical, environmental and materials chemistry can often play important roles in responding to these changes and incontinuing to help with the improvement of food safety and security. These five co-editors bring their respective expertise to the subject of the food system and the chemical advancements behind it.

Water is the most crucial material for human survival, after air. Without water, life would not be possible. It is important to know how much water is available to us and how much water is polluted. We need to monitor pollutants vigorously, both at point and nonpoint sources, using advanced analytical techniques that can monitor ultra-trace amounts of contaminants. Water reclamation is an absolute necessity today because we have contaminated our surface water, andeven groundwater in some cases, to a point that it is not clean enough for drinking or cooking. Most importantly, water must be used judiciously, and equal treatment must be paid to the reclamation and treatment of contaminated water.This book provides information on various global water challenges and solutions. We face many water challenges in terms of availability, quality, and sustainability (Chapter 1). There is an urgent need to find ways to make water more sustainable. To achieve this objective, we will have to address scientific, technical, economic, and social issues.