Shimshon Belkin - Böcker

The importance of combating infectious diseases has received international attention, p- viding the opportunity for a multidisciplinary approach that combines medicine with other scienti?candtechnologicalcapabilities,notablyinformationtechnology,nanotechnology,and biotechnology. In fact, it has been predicted that the future will bring a merging of these te- nologies with the cognitive and behavioral sciences—major forces that have the potential to balancetheworld’sinequities.Thescienti?ccommunityandworldleadersmustworktogether to use knowledge and its applications to improve the condition of the planet. The connection between infectious diseases and the oceans provides a paradigm for this perspective. A stark global context indisputably frames all human health issues in the twenty-?rst century: the world wide movement of people and goods. Throughout the past half century, international travel has skyrocketed; there are more than 500 million international arrivals per year. The greatest increase has taken place since the mid-1990s. The world has become integrated and global; consequently, the notion that it is possible to successfully eradicate a disease from the face of the planet has become simplistic. Infectious disease is a moving target and climate shifts will affect any disease that has an environmentally sensitive stage or vector. Recognizingsignalsfromclimatemodelsandincorporatingthemintohealthmeasurescanp- videnewopportunitiesforproactive—ratherthanreactive—approachestopublichealth.Thus, careful attention to the role of the oceans in human health can offer new avenues of research that will provide new means of predicting and preventing those diseases that are rooted in the environment. In this volume, pathogens in the sea are reviewed by ColinMunn, who provides a broader perspective for the topic of pathogenic microorganisms associated with the world oceans.

The importance of combating infectious diseases has received international attention, p- viding the opportunity for a multidisciplinary approach that combines medicine with other scienti?candtechnologicalcapabilities,notablyinformationtechnology,nanotechnology,and biotechnology. In fact, it has been predicted that the future will bring a merging of these te- nologies with the cognitive and behavioral sciences—major forces that have the potential to balancetheworld’sinequities.Thescienti?ccommunityandworldleadersmustworktogether to use knowledge and its applications to improve the condition of the planet. The connection between infectious diseases and the oceans provides a paradigm for this perspective. A stark global context indisputably frames all human health issues in the twenty-?rst century: the world wide movement of people and goods. Throughout the past half century, international travel has skyrocketed; there are more than 500 million international arrivals per year. The greatest increase has taken place since the mid-1990s. The world has become integrated and global; consequently, the notion that it is possible to successfully eradicate a disease from the face of the planet has become simplistic. Infectious disease is a moving target and climate shifts will affect any disease that has an environmentally sensitive stage or vector. Recognizingsignalsfromclimatemodelsandincorporatingthemintohealthmeasurescanp- videnewopportunitiesforproactive—ratherthanreactive—approachestopublichealth.Thus, careful attention to the role of the oceans in human health can offer new avenues of research that will provide new means of predicting and preventing those diseases that are rooted in the environment. In this volume, pathogens in the sea are reviewed by ColinMunn, who provides a broader perspective for the topic of pathogenic microorganisms associated with the world oceans.

Table of ContentsReporter cells: - Yeast Based Sensorsby Mifumi Shimomura-Shimizu and Isao Karube- Mammalian Cell-Based Sensor Systemsby Pratik Banerjee, Briana Franz, and Arun K. Bhunia- Fluorescent and Bioluminescent Cell-Based Sensors: Strategies for Their Preservationby Amol Date, Patrizia Pasini, and Sylvia Daunert- Electrochemical Cell-Based Sensorsby Eliora Z. Ron and Judith Rishpon- Microbial Cell Arrays by Tal Elad, Jin Hyung Lee, Man Bock Gu, and Shimshon BelkinDevices:- Surface Functionalization for Protein and Cell Patterningby Pascal Colpo , Ana Ruiz , Laura Ceriotti , and François Rossi- Fiber-Optic Based Cell Sensorsby Evgeni Eltzov and Robert S. Marks- Electronic Interfacing with Living Cellsby James T. Fleming- On-Chip Detection of Cellular Activityby R. Almog , R. Daniel , S. Vernick , A. Ron , H. Ben-Yoav, and Y. Shacham-Diamand

Applications:- Applications of Microbial Cell Sensors, by Mifumi Shimomura-Shimizu and Isao Karube- Whole-Cell Bioreporters for the Detection of Bioavailable Metals, by Anu Hynninen and Marko Virta- Bacteriophage-Based Pathogen Detection, by Steven Ripp- Cell-Based Genotoxicity Testing, by Georg Reifferscheid and Sebastian Buchinger- Cytotoxicity and Genotoxicity Reporter Systems Based on the Use of Mammalian Cells, by Christa Baumstark-Khan, Christine E. Hellweg, and Günther Reitz- Live Cell Optical Sensing for High Throughput Applications, by Ye Fang- Cyanobacterial Bioreporters as Sensors of Nutrient Availability, by George S. Bullerjahn, Ramakrishna Boyanapalli, Mark J. Rozmarynowycz, and R. Michael L. McKay- Application of Microbial Bioreporters in Environmental Microbiology and Bioremediation, by E. E. Diplock , H. A. Alhadrami , and G. I. Paton

Table of ContentsReporter cells: - Yeast Based Sensorsby Mifumi Shimomura-Shimizu and Isao Karube- Mammalian Cell-Based Sensor Systemsby Pratik Banerjee, Briana Franz, and Arun K. Bhunia- Fluorescent and Bioluminescent Cell-Based Sensors: Strategies for Their Preservationby Amol Date, Patrizia Pasini, and Sylvia Daunert- Electrochemical Cell-Based Sensorsby Eliora Z. Ron and Judith Rishpon- Microbial Cell Arrays by Tal Elad, Jin Hyung Lee, Man Bock Gu, and Shimshon BelkinDevices:- Surface Functionalization for Protein and Cell Patterningby Pascal Colpo , Ana Ruiz , Laura Ceriotti , and François Rossi- Fiber-Optic Based Cell Sensorsby Evgeni Eltzov and Robert S. Marks- Electronic Interfacing with Living Cellsby James T. Fleming- On-Chip Detection of Cellular Activityby R. Almog , R. Daniel , S. Vernick , A. Ron , H. Ben-Yoav, and Y. Shacham-Diamand

Applications:- Applications of Microbial Cell Sensors, by Mifumi Shimomura-Shimizu and Isao Karube- Whole-Cell Bioreporters for the Detection of Bioavailable Metals, by Anu Hynninen and Marko Virta- Bacteriophage-Based Pathogen Detection, by Steven Ripp- Cell-Based Genotoxicity Testing, by Georg Reifferscheid and Sebastian Buchinger- Cytotoxicity and Genotoxicity Reporter Systems Based on the Use of Mammalian Cells, by Christa Baumstark-Khan, Christine E. Hellweg, and Günther Reitz- Live Cell Optical Sensing for High Throughput Applications, by Ye Fang- Cyanobacterial Bioreporters as Sensors of Nutrient Availability, by George S. Bullerjahn, Ramakrishna Boyanapalli, Mark J. Rozmarynowycz, and R. Michael L. McKay- Application of Microbial Bioreporters in Environmental Microbiology and Bioremediation, by E. E. Diplock , H. A. Alhadrami , and G. I. Paton