Sir Michael J. Rutter – författare

Much research has attempted to show direct linear relations between genes and disorder. However, scientists have been discouraged by inconsistent findings based on this simple gene-phenotype approach. The alternative approach is to incorporate information about the environment. A gene-environment interaction approach assumes that environmental pathogens cause disorder, whereas genes influence susceptibility to environmental pathogens.

This book brings together contributions from experts from multiple disciplines who discuss:

How epidemiological cohort studies can better integrate physiological (mechanistic) measures; How best to characterise subjects’ vulnerability versus resilience by moving beyond single genetic polymorphisms; How gene hunters can benefit from recruiting samples selected for known exposures; How environmental pathogens can be used as tools for gene hunting; How to deal with potential spurious (statistical) interactions, and How genes can help explain fundamental demographic properties of disorders (e.g. sex distribution, age effects).

In this major new book, eminent scientist Professor Sir Michael Rutter gets behind the hype of the behavioral genetics debate to provide a balanced and authoritative overview of the genetic revolution and its implications for understanding human behavior. Written by one of the world''s leading figures in child psychology and psychiatry, Professor Sir Michael Rutter Provides non-technical explanation of genetics to diffuse the sensational debates surrounding the topic Sets out in layman''s terms what genes do, how much is nature and how much is nurture Argues that nature and nurture are not truly separate and gives examples of how the two interact Looks at the implications of genetic findings for policy and practice The book will inform public debate about the implications of the Human Genome Project and, more broadly, the field of genetic science

Rutter’s Child and Adolescent Psychiatry has become an established and accepted textbook of child psychiatry. Now completely revised and updated, the fifth edition provides a coherent appraisal of the current state of the field to help trainee and practising clinicians in their daily work. It is distinctive in being both interdisciplinary and international, in its integration of science and clinical practice, and in its practical discussion of how researchers and practitioners need to think about conflicting or uncertain findings.

This new edition now offers an entirely new section on conceptual approaches, and several new chapters, including:

neurochemistry and basic pharmacology brain imaging health economics psychopathology in refugees and asylum seekers bipolar disorder attachment disorders statistical methods for clinicians

This leading textbook provides an accurate and comprehensive account of current knowledge, through the integration of empirical findings with clinical experience and practice, and is essential reading for professionals working in the field of child and adolescent mental health, and clinicians working in general practice and community pediatric settings.