Stefan Barth – författare

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

Willkommen auf New Dodge, Reisende!Was führt euch her? Illegale oder legale Geschäfte? Wobei, das interessiert eh niemanden. Ihr solltet wissen: Recht hat hier, wer als Erstes schießt. Oder wen die Syndikate riechen mögen.Seid ihr etwa Kopfgeldjäger? Dann findet ihr sicher einen Job. Und zum Feierabend geht es in einen unserer zahlreichen Saloons. Dort finden einsame Herzen alles, wonach sie sich sehnen. Unsere Wüstenblumen sind die schönsten, aber auch die kratzigsten. Warnen muss ich jedoch vor den Pokertischen, denn hier ist jeder für sein Blatt selbst verantwortlich.Dann mal los – hinein ins Abenteuer! Und keine Sorge, unser Bestatter hat eure Maße schon von mir bekommen. Und sagt nicht, man hätte euch nicht gewarnt.