Stéphane Martin – Författare
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3 produkter
3 produkter
1 637 kr
Skickas inom 10-15 vardagar
This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research approaches and brain imaging in living rodents.
Del 185 - Neuromethods
Translational Research Methods in Neurodevelopmental Disorders
Häftad, Engelska, 2023
1 202 kr
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This volume explores the latest techniques used to study neurodevelopmental diseases (NDD) that range from molecular aspects to integrated research approaches and brain imaging in living rodents. Chapters in this book cover topics such as protocols to deliver shRNA in vitro and in vivo using lentiviral particles to knock-down specific protein expression; experimental procedures to use recombinant fluorescent probes to visualize endogenous proteins at the mammalian synapse; CRISPR/Cas9 toolkit to assess either gain- or loss-of-gene function in brain organoids; detailed protocols to use in vivo manipulations to correct the behavioral phenotypes in cognitive disorder mouse lines; and experimental approaches to genetically engineer macaque models of NDDs and investigate how genetic predisposition may cause neural and functional alterations. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results inyour laboratory. Cutting-edge and practical, Translational Research Methods in Neurodevelopmental Disorders is a valuable resource for all researchers who want to learn more about this important and developing field.
Del 8 - Radboud Studies in Humanities
Rural Granaries in Northern Gaul (Sixth Century BCE – Fourth Century CE)
From Archaeology to Economic History
Inbunden, Engelska, 2019
1 547 kr
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In recent years, storage has come to the fore as a central aspect of ancient economies. However studies have hitherto focused on urban and military storage. Although archaeological excavations of rural granaries are numerous, their evidence has yet to be fully taken into account. Such is the ambition of Rural Granaries in Northern Gaul (Sixth Century BCE – Fourth Century CE).Focusing on northern Gaul, this volume starts by discussing at length the possibility of quantifying storage capacities and, through them, agrarian production. Building on this first part, the second half of the book sketches the evolution of rural storage in Gaul from the Iron Age to Late Antiquity, setting firmly archaeological evidence in the historical context of the Roman Empire.