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Filled with an abundance of reader-friendly and quick-reference tables and figures, this Fourth Edition spans the etiology, epidemiology, clinical features, diagnosis, pathology, and treatment of multiple sclerosis (MS). Surpassing other texts on the topic, this reference provides recommendations and research updates from renowned authorities in the discipline and includes chapters on recent advances in neuroimaging, molecular biology, genetics, proteinomics, disease management, and combination therapy.