Suresh Rattan - Böcker

The Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health. Coverage includes the underlying mechanisms of hormesis, including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, amongst others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, along with lifestyle interventions to promote health and homoeostasis. Researchers in aging and physiology, gerontologists, clinicians and medical students will find this a valuable addition for their work.

Provides a comprehensive, scholarly review of the current state of hormesis in physiology, health, disease and aging Includes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing, novel therapeutic strategies, as well as lifestyle interventions Offers a clear understanding of hormesis' underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and more

The ambition of ageing science to discover the golden fleece of longevity and health is closely connected to the concept of 'successful ageing'. Still, for a large portion of the population, frailty and cognitive impairment is the reality of ageing, and it is by no means certain if health promotion, prevention and other interventions will reduce the probability of its occurrence.This book argues that a narrow understanding of 'successful ageing' as good health, full functioning, and active participation in society excludes a large portion of ageing individuals from the quest for a good life in old age. The challenge is that the term 'successful ageing' comes with ambitions but also with ambivalence. On the one hand, it counteracts the deficit view of ageing and facilitates visionary thinking on what might be possible in the future. On the other hand, its implicitly ageist and derogative features have negative consequences to older people and society at large. So, what is successful ageing? We provide answers at three levels: First, we synthesise the various models used to define successful ageing into a heuristic scheme able to unravel the normative complexity and differences inherent in existing models. Second, we anchor successful ageing models in a tripartite way at micro (individual), meso, and macro analytic levels of human development. Third, we argue that the usefulness of successful ageing in guiding policy will only profit from the concept, if it follows a pluralistic and holistic view without hastily deciding for one model only.

This multi-chapter book focuses on one of the hottest topics in ageing research – the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity. Hormones are an excellent system of communication between cells and tissues within an organism, and they coordinate a wide range of processes in biological systems, including neuroendocrine and immunological controls. The book offers insights into the latest significant advances in our understanding of the mechanisms of hormonal signaling that control a variety of processes involved in development and ageing.It is divided into four parts: Part I includes a review of the hundred-year history of hormones by the illustrious hormone biochemist Dr. J.R. Tata. Part II presents various chapters on the hormones involved in growth, stress and metabolism, while Part III addresses the hormones controlling cognition and rhythms in ageing processes. Lastly, Part IV discusses the hormones affecting reproduction, immunity and life span. It also explores the use of hormones as pharmaceuticals to maintain health in the elderly. It is a valuable resource for those working in the area of hormone signaling in general and in the field of ageing research in particular.

This multi-chapter book focuses on one of the hottest topics in ageing research – the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity.