Susan Masino - Böcker

Homeostasis of key metabolites and metabolic health affects all bodily systems.  Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders.  Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions.  Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition.  Adenosine:  A Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system.  Because of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism.  At the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression.  Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function.  Leaders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders.  This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.

AC/DC FAQ spans AC/DC's 40-year career, starting from the band's inception in 1973. This book covers everything from their early days in Australia to their first tour of England and the United States. It also includes personal experiences, stories, conversations, and interviews by author Susan Masino, who has known the band since 1977.Featuring 37 chapters, AC/DC FAQ chronicles the personal history of each of the band members, all their albums, tours, and various anecdotes. Rebounding from the tragic loss of their singer Bon Scott in 1980, AC/DC hired Brian Johnson and went on to record Back in Black, which is now one of the top five biggest-selling albums in music history. Taking a seven-year break after their album Stiff Upper Lip, the band came back in the fall of 2008 with a new album, Black Ice, and a tour that ran from 2008 through the summer of 2010. Once again breaking records, AC/DC saw the Black Ice Tour become the second-highest-grossing tour in history. True rockers from the very beginning, AC/DC will continue to be heralded as one of the greatest rock and roll bands of all time.

Homeostasis of key metabolites and metabolic health affects all bodily systems.  Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders.  Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions.  Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition.  Adenosine:  A Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system.  Because of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism.  At the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression.  Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function.  Leaders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders.  This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.

Covering three generations of Hank Williams, Family Tradition is both unique and vast in scope. Beginning in the present day with Hank III – who gave the author unprecedented access – and time-traveling across the years, this examines just what kind of rebel mojo inspired this crazed family of country music, from Hank Sr. – often regarded as one of the most influential of American musicians – to Hank Jr., to this year's model, Hank III, who has somehow found a way to reconcile his legacy's deep-rooted twang and high-lonesome sound with particularly searing strains of punk and heavy metal, launching an all-out war with traditional Nashville in the process.Listen to Susan Masino live at Book Expo America on the BEA Podcast.