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2 produkter
2 produkter
Inbunden, Engelska, 2005
3 811 kr
Skickas inom 5-8 vardagar
With contributions from an international team of leading researchers, the book pulls together updated research results in the area of HIV/AIDS modeling to provide readers with the latest information in the field. Topics covered include: AIDS epidemic models; vaccine models; models for HIV/cell dynamics and interactions; cellular kinetics; viral dynamics with antiviral treatments; modeling of drug resistance and quasispecies.Extensive deterministic models, statistical models, stochastic models and state space models on treating AIDS patients with anti-retroviral drugs are provided, as well as an in-depth discussion of these models. The book also contains updated reviews on mathematical models for assessing effects of AIDS vaccines, statistical methods for analyzing clinical trial data on AIDS vaccines, and overviews of models and statistical methods for assessing drug resistance of HIV to anti-retroviral drugs. Some important statistical methods specific to the intervention and prevention of HIV epidemic are also discussed.This will be a useful reference source for graduate students and researchers in biomathematics and biostatistics, as well as for HIV/AIDS epidemiologists and clinical investigators learning quantitative methods to study AIDS epidemics and HIV infection.
Del 9 - Series In Mathematical Biology And Medicine
Handbook Of Cancer Models With Applications
Inbunden, Engelska, 2008
3 390 kr
Tillfälligt slut
Composed of contributions from an international team of leading researchers, this book pulls together the most recent research results in the field of cancer modeling to provide readers with the most advanced mathematical models of cancer and their applications.Topics included in the book cover oncogenetic trees, stochastic multistage models of carcinogenesis, effects of ionizing radiation on cell cycle and genomic instability, induction of DNA damage by ionizing radiation and its repair, epigenetic cancer models, bystander effects of radiation, multiple pathway models of human colon cancer, and stochastic models of metastasis. The book also provides some important applications of cancer models to the assessment of cancer risk associated with various hazardous environmental agents, to cancer screening by MRI, and to drug resistance in cancer chemotherapy. An updated statistical design and analysis of xenograft experiments as well as a statistical analysis of cancer occult clinical data are also provided.The book will serve as a useful source of reference for researchers in biomathematics, biostatistics and bioinformatics; for clinical investigators and medical doctors employing quantitative methods to develop procedures for cancer diagnosis, prevention, control and treatment; and for graduate students.