Structural genomics is a newly emerging field that has arisen following the successful footsteps of the major sequencing efforts generally bundled under the heading "genomics". In Structural Proteomics: High Throughput Methods, readers are provided with a current view of all aspects of the ''pipeline'' that takes protein targets to structures and how these have been optimized. This volume includes chapters describing in-depth the individual steps in the Structural Genomics pipeline, as well as overviews of individual Structural Genomics initiatives. Topics include Target Selection for structural genomics, Protein structure modeling, High-throughput cloning, Mass Spectrometry modeling. Structural Proteomics: High Throughput Methods, encourages its readers to access further details on the methodologies in on-line resources as well as in cited literature making it an invaluable resource. Most methods in this important book are as amenable to small laboratories as to large consortia, and do not require major investments in facilities. This essential volume provides insight into the diversity of approaches adopted by different laboratories and proves that ''high throughput'' is really the defining characteristic of structural genomics.

For decades, the climber and extreme mountaineer Thomas Huber has been teetering on the edge, always at the limit. He recorded great success in first ascents and spectacular climbing tours that no one had dared to do before. He has suffered defeats and has survived serious accidents and a kidney tumor — but through every challenge and failure, he has had the strength to always get back up.In his autobiography, Huber talks about his childhood at the foot of the Alps, about the power of the first step, about passion, courage, and doubt. This book is both the story of one of the most famous mountaineers of our time and a hymn to freedom.

Structural genomics is a newly emerging field that has arisen following the successful footsteps of the major sequencing efforts generally bundled under the heading "genomics". In Structural Proteomics: High Throughput Methods, readers are provided with a current view of all aspects of the ''pipeline'' that takes protein targets to structures and how these have been optimized. This volume includes chapters describing in-depth the individual steps in the Structural Genomics pipeline, as well as overviews of individual Structural Genomics initiatives. Topics include Target Selection for structural genomics, Protein structure modeling, High-throughput cloning, Mass Spectrometry modeling. Structural Proteomics: High Throughput Methods, encourages its readers to access further details on the methodologies in on-line resources as well as in cited literature making it an invaluable resource. Most methods in this important book are as amenable to small laboratories as to large consortia, and do not require major investments in facilities. This essential volume provides insight into the diversity of approaches adopted by different laboratories and proves that ''high throughput'' is really the defining characteristic of structural genomics.

For decades, the climber and extreme mountaineer Thomas Huber has been teetering on the edge, always at the limit. He recorded great success in first ascents and spectacular climbing tours that no one had dared to do before. He has suffered defeats and has survived serious accidents and a kidney tumor — but through every challenge and failure, he has had the strength to always get back up.In his autobiography, Huber talks about his childhood at the foot of the Alps, about the power of the first step, about passion, courage, and doubt. This book is both the story of one of the most famous mountaineers of our time and a hymn to freedom.