Thomas J. Colacot – författare
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4 produkter
4 produkter
3 202 kr
Skickas inom 10-15 vardagar
This volume gives an overview of the applications of organometallic chemistry in process chemistry relevant to the current topics in synthetic chemistry. This volume starts with an introduction on the historical development of organometallics in process chemistry and is followed by chapters dealing with the last five years’ development in various organometallic reaction types such as the challenging cross coupling process, construction of 3.1.0 bicycles, pressure and transfer hydrogenations of historically challenging compounds such as esters, utilization of carbon dioxide for making organic compounds by flow process, drug synthesis and metal detection and scavenging in the finished APIs. A chapter by Colacot et.al., is also devoted to the process development and structural understanding of organometallic catalysts with particular emphasis to LnPd(0) catalysts. An academia – industry collaborated chapter on the use of water as a solvent for organometallic processes is included in this book.
3 202 kr
Skickas inom 10-15 vardagar
This volume gives an overview of the applications of organometallic chemistry in process chemistry relevant to the current topics in synthetic chemistry. This volume starts with an introduction on the historical development of organometallics in process chemistry and is followed by chapters dealing with the last five years’ development in various organometallic reaction types such as the challenging cross coupling process, construction of 3.1.0 bicycles, pressure and transfer hydrogenations of historically challenging compounds such as esters, utilization of carbon dioxide for making organic compounds by flow process, drug synthesis and metal detection and scavenging in the finished APIs. A chapter by Colacot et.al., is also devoted to the process development and structural understanding of organometallic catalysts with particular emphasis to LnPd(0) catalysts. An academia – industry collaborated chapter on the use of water as a solvent for organometallic processes is included in this book.
2 794 kr
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Dieser Band gibt einen Überblick über die Anwendungen der metallorganischen Chemie in der Prozesschemie, die für die aktuellen Themen der synthetischen Chemie relevant sind. Der Band beginnt mit einer Einleitung über die historische Entwicklung der Organometallchemie in der Prozesschemie, gefolgt von Kapiteln, die sich mit den Entwicklungen der letzten fünf Jahre bei verschiedenen metallorganischen Reaktionstypen befassen, wie dem anspruchsvollen Kreuzkupplungsprozess, der Konstruktion von 3.1. 0-Fahrrädern, Druck- und Transfer-Hydrierungen von historisch anspruchsvollen Verbindungen wie Estern, der Nutzung von Kohlendioxid für die Herstellung organischer Verbindungen im Durchflussverfahren, der Arzneimittel-Synthese und der Metalldetektion und -reinigung in den fertigen APIs Ein Kapitel von Colacot et.al. ist der Verfahrensentwicklung und dem strukturellen Grundverständnis von metallorganischen Katalysatoren gewidmet, wobei der Schwerpunkt auf LnPd(0)-Katalysatoren liegt Das Buch enthält ein Kapitel über die Verwendung von Wasser als Lösungsmittel für organometallische Prozesse, das in Zusammenarbeit zwischen Wissenschaft und Industrie durchgeführt wurde.
1 014 kr
Skickas inom 11-20 vardagar
Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more. -Includes rare industrial case studies difficult to find in current literature -Helps readers successfully carry out their own reactions -Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation -Features a foreword by Nobel Laureate R. H. Grubbs -A perfect resource for every R&D researcher in industry -Useful for PhD students and postdocs: excellent preparation for a job interview Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.