Thomas Thum - Böcker

This volume describes important functions and roles of micro RNAs in the vasculature in health, disease, therapeutics and diagnostics. It shows how miRNAs can be used to improve stem cell-based regenerative therapies of cardiovascular diseases; further the role of miRNAs as regulators in lipoprotein metabolism in the liver and reverse cholesterol transport is depicted, as well as their pathological function in diabetes and atherosclerosis. The book discusses the use of circulating miRNAs as disease biomarkers and shows interesting correlations with the amount of detectable miRNAs in the blood and future cardiovascular risks.This book is edited and written by leading figures in the field and will be an invaluable resource for academics, researchers and students working on non-coding RNAs in biomedicine, physiology and vascular biology.

This book is a self-contained, practical introduction how to use FeatureIDE for modeling and implementing variable systems. In particular, readers learn how to analyze domains using feature models, specify requirements in form of configurations, and how to generate code based on conditional compilation and feature-oriented programming. Given the interactive style of the book, readers can directly try out the open-source development environment. All code examples are available in the standard distribution on GitHub and can immediately been used for individual modifications. Each part of the book is presented as a step-by-step tutorial and additionally illustrated using an ongoing example of elevator control software written in Java.Written by the core development team of FeatureIDE, this book is suitable for students using a tool for deepening the theoretical foundations of variability modeling and implementation, and as a reference for practitioners needing a stable and scalable tool for industrial applications. FeatureIDE is the most used open-source tool for feature modeling and has been continuously improved since 2004. The success of FeatureIDE is due to being a vehicle for cutting-edge product-line research by still providing an easy-to-use and seamless integration into Eclipse.