Tony Auffret - Böcker

Freeze-drying, in the past popular in the food industry, has more recently been adopted by the pharmaceutical industry as a standard method for the production of stable solid preparations. Freeze-drying of Pharmaceuticals and Biopharmaceuticals is the first book to specifically describe this process, as related to the pharmaceutical industry. The emphasis of this book is on the properties of the materials processed, how effective formulations are arrived at, and how they are stored and marketed. Beginning with a historical overview of the process, Freeze-drying of Pharmaceuticals and Biopharmaceuticals briefly describes the processes and equipment involved, including: the physics, chemistry and biochemistry associated with freezing, aspects of formulation development, primary and secondary drying; the economics and engineering of scaling up; and, most importantly, attributes of the dried product. It also discusses in detail the science behind freeze-drying, such as the properties of crystalline and amorphous solids. The book concludes with selected case studies and discusses the future of freeze-drying, advances in alternative drying methods, and concludes with an extensive bibliography. This book, written by a leading expert in the field, is aimed primarily at product and process developers in the biopharmaceutical industry and academia.

HIGH EXPLOSIVES YOU CAN STOCKPILE, NUCLEAR WEAPONS YOU CAN STOCKPILE, CHEMICAL WARFARE AGENTS YOU CAN STOCKPILE, BIOLOGICAL WEAPONS YOU CANNOT. The year is 1991, and the Soviet Union is in a state of collapse. But with chaos reigning in Europe and secrets being leaked all too easily from the Ministry of Defence, why should the British Security Services be interested when the premises of a small biotech start-up are burgled, resulting in an accidental death? Complete with suspected Russian spies and biological warfare, this peculiar case proves more complex to solve than anticipated, and truth and trust are tormented by doubt and deception as the path of the small unit of MI5 agents investigating the case is criss-crossed by innocence and subterfuge, bluff and bullying.

"We lead a quiet life. Talking to people, building up a picture. Like a jigsaw. And just like a jigsaw, we spend a lot of time sorting out pieces of sky. They may seem dull and uninteresting, but we can't leave them out." Is a virus that takes up to eight weeks for symptoms to appear, and kills only 10% of infected people, really the perfect terrorist bioweapon?In this sequel to The Death of a Smoker, four years have passed since Quinton Bickley-Morris, a suspected spy and adversary of the Tufton Street team, slipped out of the country undetected. After a chance sighting, Harry Nevile and his team are desperate to go after him, but the more immediate threat of a suspected terrorist attack on the government takes priority. As Harry's team investigates, piecing together fragments of evidence, the truth is gradually revealed, and it is far closer to home than they could ever have anticipated.