Torsten Zuberbier – författare

Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.

Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.

Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.

Urticaria is one of the most common diseases encountered in dermatology. The fleeting nature of wheals often makes a first diagnosis by both patients and physicians seem easy. The disease itself is of a highly complex nature, with a variety of clinical manifestations ranging from pinpoint sized wheals to extensive angioedema. Further complexities include the diversity of possible eliciting and aggravating factors, the many different clinical subtypes and the therapeutic responsiveness.This second, extensively revised edition includes the indications listed in the most recent international guidelines, provides a practical, comprehensive review of all clinical aspects and causes, and addresses the diagnosis and therapy of different types of urticaria. Specific chapters are devoted to classification, aetiopathogenesis, patient reported outcomes, acute urticaria, chronic urticaria and its comorbidities, angioedema without weals, inducible urticarias, special populations including children, treatment with antihistamines and omalizumab, other interventions and looking ahead to new therapies. This new edition is a must read for dermatologists, allergists, pediatricians and practitioners of all disciplines who want their patients to benefit from cutting-edge diagnostics and treatments.

Urticaria is one of the most common diseases encountered in dermatology. The fleeting nature of wheals often makes a first diagnosis by both patients and physicians seem easy. The disease itself is of a highly complex nature, with a variety of clinical manifestations ranging from pinpoint sized wheals to extensive angioedema. Further complexities include the diversity of possible eliciting and aggravating factors, the many different clinical subtypes and the therapeutic responsiveness.This second, extensively revised edition includes the indications listed in the most recent international guidelines, provides a practical, comprehensive review of all clinical aspects and causes, and addresses the diagnosis and therapy of different types of urticaria. Specific chapters are devoted to classification, aetiopathogenesis, patient reported outcomes, acute urticaria, chronic urticaria and its comorbidities, angioedema without weals, inducible urticarias, special populations including children, treatment with antihistamines and omalizumab, other interventions and looking ahead to new therapies. This new edition is a must read for dermatologists, allergists, pediatricians and practitioners of all disciplines who want their patients to benefit from cutting-edge diagnostics and treatments.

Urticaria is one of the most common diseases in dermatology and allergy. Unlike many other diseases, the ? eeting nature of the wheals makes ? rst diagnosis by both patients and phy- cians in many cases easy. However, this only refers to the ordinary wheals. The disease itself is highly complex in nature, with variety of clinical manifestations ranging from pinpoi- sized wheals to extensive angiodema. Complexity is also seen in the diversity of possible eliciting factors, the many different clinical subtypes and the therapeutic responsiveness. Only in recent years has a better understanding of the diversity in the different subtypes led to new classi? cations and new evidence-based guidelines for diagnostics and mana- ment of the disease. While mast cells are in the center of most urticaria reactions, it is now clearly understood that the responsible mediators are not only limited to histamines. The current book appears in a series of books by Springer. In 1986, the ? rst monograph was edited by Professor Henz née Chanewsky. Since then, two updates of the book have appeared in the German language with Professor Henz as ? rst editor and T. Zuberbier, J. Grabbe, and E. Monroe as the co-editors of the most recent English version, published in 1998. All these books have been written as a joint effort of Professor Henz together with her team at the Department of Dermatology at the Virchow Clinic, Humboldt University, Berlin.

Urticaria is one of the most common dermatological and allergological cutaneous reactions and, compared to other diseases, it is easily recognized by patients and physicians alike. Nevertheless, the disease is highly complex regarding its eliciting causes, its clinical manifestations and its therapy. Thus, a famous New York dermatologist once mentioned that he would rather have a lion than a patient with chronic urticaria walk into his office. This may seem surprising since, to the uninitiated, different types of urticaria look alike, and the pathomechanisms are rather well understood, with mast cells being almost invariably the main effector cells. In 1986, a monograph of the first editor (Prof. Czarnetzki, now with the married name Henz) appeared, giving a detailed and thorough review of the then current state of knowledge regarding all aspects of the disease. Since then, two updates of this book have appeared in the German language, with coworkers of the clinic of Prof. Henz helping in the revision of the various chapters of the old monograph, and with particular emphasis on practical aspects of the disease. The present book is mainly a translation of the second German edition, with only minor updates and with more citations from the literature since the 1986 monograph is no longer available for purchase.

Urticaria is one of the most common dermatological and allergological cutaneous reactions and, compared to other diseases, it is easily recognized by patients and physicians alike. Nevertheless, the disease is highly complex regarding its eliciting causes, its clinical manifestations and its therapy. Thus, a famous New York dermatologist once mentioned that he would rather have a lion than a patient with chronic urticaria walk into his office. This may seem surprising since, to the uninitiated, different types of urticaria look alike, and the pathomechanisms are rather well understood, with mast cells being almost invariably the main effector cells. In 1986, a monograph of the first editor (Prof. Czarnetzki, now with the married name Henz) appeared, giving a detailed and thorough review of the then current state of knowledge regarding all aspects of the disease. Since then, two updates of this book have appeared in the German language, with coworkers of the clinic of Prof. Henz helping in the revision of the various chapters of the old monograph, and with particular emphasis on practical aspects of the disease. The present book is mainly a translation of the second German edition, with only minor updates and with more citations from the literature since the 1986 monograph is no longer available for purchase.