Trideva Sastri Koduru – författare

The Neurodegeneration Revolution: Emerging Therapies and Sustainable Solutions provides insights into the mechanics, characteristics, behavior, application, and manufacturing of advanced materials such as nanowires, 2D materials, biomaterials, smart materials, and more. The first section discusses the mechanics and electronic and magnetic properties of nanomaterials, photonic, and photonic materials and devices, 2D magnetic materials, smart materials and coatings, metamaterials, and microdevices and sensors. The second section of the book covers manufacturing technologies and methods of previously discussed materials, outlining manufacturing techniques for additive manufacturing of metallic lattice structures, biomedical alloys, shape memory alloys, multifunctional polymer composites, nanocomposite structures, ceramics, and batteries.Explores emerging therapies such as gene therapy, stem cell therapy, and nanoparticle-mediated drug delivery, as well as sustainable green nanotechnologyOffers practical guidance for healthcare professionals and caregivers on how to effectively manage neurodegenerative diseasesExplores the application of Artificial Intelligence and Machine Learning in the treatment of neurodegenerative diseases

The Neurodegeneration Revolution: Emerging Therapies and Sustainable Solutions provides insights into the mechanics, characteristics, behavior, application, and manufacturing of advanced materials such as nanowires, 2D materials, biomaterials, smart materials, and more. The first section discusses the mechanics and electronic and magnetic properties of nanomaterials, photonic, and photonic materials and devices, 2D magnetic materials, smart materials and coatings, metamaterials, and microdevices and sensors. The second section of the book covers manufacturing technologies and methods of previously discussed materials, outlining manufacturing techniques for additive manufacturing of metallic lattice structures, biomedical alloys, shape memory alloys, multifunctional polymer composites, nanocomposite structures, ceramics, and batteries.- Explores emerging therapies such as gene therapy, stem cell therapy, and nanoparticle-mediated drug delivery, as well as sustainable green nanotechnology- Offers practical guidance for healthcare professionals and caregivers on how to effectively manage neurodegenerative diseases- Explores the application of Artificial Intelligence and Machine Learning in the treatment of neurodegenerative diseases

Neurodegenerative disorders are rising worldwide, yet most approved drugs merely temper symptoms. Nucleic Acids and Precision Therapies for Neuroprotection addresses this therapeutic shortfall directly, tracing how antisense oligonucleotides, RNA interference agents, mRNA platforms, aptamers, and CRISPR-class editors are redefining what "treatable" means for Alzheimer’s, Parkinson’s, ALS, Huntington’s disease, and Multiple Sclerosis.Rather than cataloguing modalities in isolation, the book lays out an end-to-end translational roadmap from target identification and sequence optimisation to blood–brain barrier traversal, immunogenicity management, scalable manufacturing, and ethical oversight. Delivery science (including viral, nanoparticle, and hybrid vectors), AI-enabled biomarker discovery, adaptive trial architectures, and shifting global regulatory frameworks are viewed as interlocking elements of a single development pathway.By aligning disparate scientific "dialects" into a shared, practice-oriented language, Nucleic Acids and Precision Therapies for Neuroprotection offers what the field currently lacks: a cohesive guide for moving nucleic acid therapeutics from concept to clinic with precision. Researchers, clinicians, regulators, and industry teams will find pragmatic frameworks, comparative tables, and decision points that shorten the path between mechanistic insight and patient impact without sacrificing rigour or transparency.KEY FEATURES:Integrates molecular design, delivery engineering, clinical trial strategy, and regulatory science into one end-to-end translational workflow for nucleic acid therapeutics in neurologyDelivers disease-specific playbooks (AD, PD, ALS, HD, MS) that map genotype/phenotype data to actionable targets, modality selection, and delivery routesEmbeds AI/ML-driven biomarker discovery, patient stratification, and manufacturability analytics alongside ethical, access, and cost considerations

Neurodegenerative disorders are rising worldwide, yet most approved drugs merely temper symptoms. Nucleic Acids and Precision Therapies for Neuroprotection addresses this therapeutic shortfall directly, tracing how antisense oligonucleotides, RNA interference agents, mRNA platforms, aptamers, and CRISPR-class editors are redefining what "treatable" means for Alzheimer’s, Parkinson’s, ALS, Huntington’s disease, and Multiple Sclerosis.

Rather than cataloguing modalities in isolation, the book lays out an end-to-end translational roadmap from target identification and sequence optimisation to blood–brain barrier traversal, immunogenicity management, scalable manufacturing, and ethical oversight. Delivery science (including viral, nanoparticle, and hybrid vectors), AI-enabled biomarker discovery, adaptive trial architectures, and shifting global regulatory frameworks are viewed as interlocking elements of a single development pathway.

By aligning disparate scientific "dialects" into a shared, practice-oriented language, Nucleic Acids and Precision Therapies for Neuroprotection offers what the field currently lacks: a cohesive guide for moving nucleic acid therapeutics from concept to clinic with precision. Researchers, clinicians, regulators, and industry teams will find pragmatic frameworks, comparative tables, and decision points that shorten the path between mechanistic insight and patient impact without sacrificing rigour or transparency.

KEY FEATURES:

Integrates molecular design, delivery engineering, clinical trial strategy, and regulatory science into one end-to-end translational workflow for nucleic acid therapeutics in neurology Delivers disease-specific playbooks (AD, PD, ALS, HD, MS) that map genotype/phenotype data to actionable targets, modality selection, and delivery routes Embeds AI/ML-driven biomarker discovery, patient stratification, and manufacturability analytics alongside ethical, access, and cost considerations