Vijay Kothari – författare
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29 produkter
29 produkter
E-bok
PDF, Engelska, 2012389 kr
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Scientific Study from the year 2012 in the subject Biology - Micro- and Molecular Biology, grade: A, Nirma University, course: M.Sc., language: English, abstract: This study aimed at investigating the effect of low power (90 W) microwave radiation (2450 MHz) on microbial growth, enzyme activity (protease and urease), and aflatoxin production. Thermal effect was avoided by keeping inoculum in ice while treating with microwave (for varying duration i.e. 2, 4, and 6 min). After 6 min MW treatment to S. aureus, its growth was stimulated over control by ~10%. Total protease activity in Aeromonas hydrophila witnessed a 33% decrease as compared to control after a microwave exposure of 2 min. Similar decrease of 24% in total protease activity of Candida albicans was observed after microwave exposure of 6 min. Staphylococcus aureus lost its urease activity completely after microwave treatment. Aflatoxin production was completely inhibited in Aspergillus parasiticus after microwave exposure of 2, 4, and 6 min. However, it required a 6 min microwave exposure for complete inhibition of aflatoxin production in Aspergillus flavus. Our results positively suggest existence of microwave specific non-thermal effect on microbial growth and metabolism.
Häftad, Engelska, 2012
863 kr
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E-bok
PDF, Engelska, 201216 kr
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Scientific Study from the year 2012 in the subject Biology - Micro- and Molecular Biology, Nirma University (Institute of Science), language: English, abstract: Five halotolerant bacteria were isolated from saline soil of Gujarat. Their identification and characterization with respect to optimum pH and salt concentration, and metal tolerance was carried out. Among all isolates Virgibacillus marismortui exhibited better metal tolerance/resistance. In certain cases stimulatory effect of metal ions on growth was also observed. Such organisms can serve as a good model for study of stress response among prokaryotes, and can also be explored for their potential of bioremediation of metal polluted saline sites with alkaline pH.
Häftad, Engelska, 2012
516 kr
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E-bok
PDF, Engelska, 2012480 kr
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Scientific Study from the year 2012 in the subject Biology - Micro- and Molecular Biology, Nirma University (Institute of Science), language: English, abstract: Extracts of five different plant seeds- Syzygium cumini, Pheonix sylvestris, Manilkara zapota, Tamarindus indica, and Annona squamosa- prepared by Microwave Assisted Extraction (MAE) method were screened for their antimicrobial activity against certain phytopathogenic microorganisms. Ethanolic extract of S. cumini was found to possess highest average total activity against susceptible microbes. Total activity was found to have a positive correlation with the extraction efficiency. Methanolic extract of T. indica exerted bactericidal action against Agrobacterium tumefaciens and Pseudomonas syringae. Ethanolic extract of P. sylvestris was able to protect cabbage leaf against Xanthomonas campestris. Acetone extract of M. zapota was able to reduce aflatoxin production in Aspergillus parasiticus by >50 %. Curcumin proved bactericidal against X. campestris.
Häftad, Engelska, 2012
824 kr
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E-bok
PDF, Engelska, 2014481 kr
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Scientific Study from the year 2013 in the subject Biology - Micro- and Molecular Biology, grade: A, Nirma University (Institute of Science), course: Microbiology, language: English, abstract: Extracts of Emblica officinalis seeds prepared by Microwave Assisted Extraction (MAE) method were evaluated for their antimicrobial property against planktonic form of certain human/plant pathogenic microbes. Additionally, seed extracts of E. officinalis, Tamarindus indica, Manilkara zapota, Phoenix sylvestris, Syzygium cumini, and selected phytocompounds were tested against multi-drug resistant Streptococcus mutans (a major pathogen associated with human dental caries) in its planktonic as well as biofilm form. Ability of these extracts to eradicate and kill S. mutans biofilm was investigated. E. officinalis extracts exerted bactericidal action against S. mutans, Pseudomonas aeruginosa, and Vibrio cholerae. Acetone extract of S. cumini, and curcumin were able to inhibit S. mutans at appreciably low concentrations of 50 ug/mL and 20 ug/mL respectively. T. indica and S. cumini seed extracts were able to kill = 80% cells of S. mutans in biofilm, in the concentration range of 500-1000 ug/mL. These extracts were able to achieve = 95% killing of S. mutans biofilm at concentrations ranging from 600-2000 ug/mL. Ability of the potent extracts to kill S. mutans biofilm did not seem to be much dependent on eradication of the biofilm. Extraction efficiency was found to have a good correlation with antibacterial activity.
Häftad, Engelska, 2014
863 kr
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Häftad, Engelska, 2014
516 kr
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E-bok
PDF, Engelska, 2014247 kr
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Scientific Study from the year 2013 in the subject Biology - Micro- and Molecular Biology, grade: A, Nirma University (Institute of Science), language: English, abstract: Hydrocarbon contamination of marine ecosystems has been a major environmental concern. Hydrocarbon metabolizing capacity of four halotolerant bacteria (Bacillus atrophaeus, Halomonas shengliensis, Halomonas koreensis, and Virgibacillus salarius) isolated from saline soil of Khambhat, India was investigated. Presence of catechol metabolizing enzymes (catechol 2,3 dioxygenase, chlorocatechol 1,2 dioxygenase, and protocatechuate 3,4 dioxygenase) was checked in V. salarius, as only this among all the test organisms could grow on the hydrocarbon substrates used, and compared with Pseudomonas oleovorans. Effect of salinity of the growth medium on activity of catechol metabolizing enzymes was also studied. Catechol 2,3 dioxygenase activity in both the organisms was more susceptible to increase in salinity of the growth medium than chlorocatechol 1,2-dioxygenase activity. To the best of our awareness, this is the first report of catechol metabolism in V. salarius. V. salarius was found to be capable of weak biofilm formation. As V. salarius is capable of growing at high salt concentration, alkaline pH, hydrocarbon degradation, and also of growth in presence of various metal ions, it can be an attractive candidate for bioremediation of marine oil spills. Organisms like V. salarius can also serve as a model for multiple stress tolerance in prokaryotes.
Häftad, Engelska, 2014
561 kr
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E-bok
PDF, Engelska, 2014464 kr
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Scientific Study from the year 2013 in the subject Biology - Micro- and Molecular Biology, grade: A, Nirma University (Institute of Science), language: English, abstract: Increasing applications of MW radiation has led to concerns globally due to the suspected bio effects associated with its exposure. Effect of MW, thermal and/or athermal, is inconclusive, complex, and controversial in literature. Thermal effect causes thermogenic effect while athermal effects are other than heat and such effects reported as somatic effect and/or genetic effect. This study basically deals with the athermal effects and is aimed at investigating the hypothesis that the exposure of microbial cells to MW (low power) may cause athermal effect, which affect on growth of microbes, enzyme activity, and production of exopolysaccharides. Furthermore, we have also checked the effect of different intracellular enzymes on MW treated bacteria. Our study also gives information that MW athermal effects causes changes at genetic level and can be passed on to next generation. There are numerous and increasing applications of MW energy and technology in the industries, in homes, in medical, research institutions etc., and there is greater awareness and concern of the public over the suspected potential health hazards associated with such exposures [ICNIRP Guidelines, 1998]. There is therefore, a need for deeper understanding of the bio-effects of exposure to this radiation. Due to the ease of handing them in laboratory, microorganisms can be conveniently used to study the effect of MW on living systems. Besides, employing mutagenic frequencies of MW radiation for microbial strain improvement can be of considerable industrial significance. Objectives:1. To investigate the effect of low power MW on,a. Growth b. Extracellular enzyme (amylase and pectinase) activity in Bacillus subtilis, Streptococcus mutans and Pectobacterium carotovora. c. Exopolysaccharide (EPS) in S. mutans and Xanthomonas campestris. 2. To study the effect of low power MW on,a. Growthb. Protein synthesisc. Intracellular enzyme (Glucose-6-phosphatase and - galactosidase) activity3. To investigate mutagenic effect of MW on EPS production in X. campestris.
E-bok
PDF, Engelska, 2015390 kr
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Scientific Study from the year 2014 in the subject Biology - Micro- and Molecular Biology, grade: A, Nirma University (Institute of Science), course: M.Sc., language: English, abstract: This study attempted at microwave mutagenesis of: (i) Lactobacillus plantarum for lactic acid overproduction, and (ii) Streptococcus mutans for reduced lactic acid production. Lactic acid is among the microbiological products with high market potential. Lactic acid is also an important virulence factor in formation of dental caries by S. mutans, as the acid produced by the bacteria leads to demineralisation of the teeth. Two of the mutants obtained (one from each organism) were able to maintain the altered lactic acid production till 10 generations. However the magnitude of alteration in lactic acid producing ability of the mutants went on decreasing over generations. The microwave effects observed in this study seem largely to be athermal in nature. Investigation of the mutants obtained at molecular level may result in identification of novel mutations responsible for altered lactic acid production. These mutations can then be introduced into a suitable organism either for better industrial production of lactic acid, or for constructing new probiotic strain(s) for possible application in maintenance of oral health. Effect of low power (90 W) microwave (2,450 MHz) radiation on bacterial growth and pigment production was studied in three different bacteria. Microwave exposure of 2-6 min duration was able to alter growth and pigment production (prodigiosin production by Serratia marcescens, violacein production by Chormobacterium violaceum, and staphyloxanthin production by Staphylococcus aureus) in the test organisms significantly. In this study, pigment production was estimated in the cell population originated from microwave treated inoculum, and not directly in the MW treated cells. Thus the alterations in pigment production and/or secretion might have been transferred from the originally MW treated cells to their daughter cells (who did not receive direct MW exposure), indicating the mutagenic influence of microwave radiation. Heavy prodigiosin overproduction observed in one of the test tubes inoculated with microwave treated S. marcescens could not be sustained by daughter populations corresponding to that tube, indicating the reversible nature of microwave induced mutation(s). The microwave effects observed in this study largely seem to be of athermal nature, as the thermal effect was minimized by use of ice during the microwave treatment.
Häftad, Engelska, 2015
753 kr
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E-bok
PDF, Engelska, 2015208 kr
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Scientific Study from the year 2014 in the subject Biology - Micro- and Molecular Biology, grade: A, Nirma University (Institute of Science), course: M.Sc., language: English, abstract: Objective: To investigate the effect of (i) seed extracts of Pongamia pinnata, Pyrus pyrifolia, and Manilkara hexandra, (ii) bacterial pigment prodigiosin, and (iii) three organic solvents (ethanol, methanol, and DMSO), on quorum sensing (QS) in Chromobacterium violaceum. Methods: C. violaceum was challenged with plant extracts prepared by microwave assisted extraction (MAE) method, prodigiosin, and organic solvents. Effect of these test substances on C. violaceum growth, and quorum sensing regulated pigment (violacein) production was studied by broth dilution assay. High performance liquid chromatography (HPLC) was also applied to generate chromatographic fingerprint of the active extracts. Effect of sub-MIC level of the antibiotic streptomycin on quorum sensing regulated pigment production was also studied. Results: P. pinnata seed extracts and prodigiosin were found to possess anti-QS, and M. hexandra and P. pyrifolia seed extracts to possess QS-enhancing effect in C. violaceum. DMSO was found to enhance violacein production, whereas ethanol and methanol reduced violacein production in C. violaceum. Streptomycin at sub-MIC level was able to significantly arrest QS-regulated pigment production in C. violaceum and S. marcescens. Conclusion: Prodigiosin and the seed extracts used in this study could affect quorum sensing in C. violaceum to a notable extent. Results of this study also emphasizes the importance of inclusion of appropriate solvent controls (negative controls) in bioassays designed for screening of antimicrobial and/or anti-QS compounds. Antipathogenic potential of low concentrations of streptomycin was also demonstrated.
Häftad, Engelska, 2015
377 kr
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Häftad, Engelska, 2015
229 kr
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Inbunden, Engelska, 2021
2 574 kr
Skickas inom 10-15 vardagar
This book presents the latest knowledge on both the physiological and the microbiological aspects of wound healing. Fresh insights into the process of cutaneous wound healing are described, which involves tissue regeneration and repair processes consisting of a sequence of molecular and cellular events. The management of infected wounds is then discussed in detail, covering the roles of traditional medicine practices, novel anti-infective formulations, non-antibiotic approaches, and probiotic bacteria. A section devoted to the interdisciplinary approach to wound care addresses topics including in vitro and in vivo research models, the development of advanced wound dressings, tissue engineering, and the potential applications of bioscaffolds. The authors are all leading researchers in the field. This book is an attempt to showcase current research status and future directions in the area of wound-healing research, which must be of interest to a large group ofreaders and researchers interested in this field.
E-bok
Engelska, 20212 941 kr
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This book presents the latest knowledge on both the physiological and the microbiological aspects of wound healing. Fresh insights into the process of cutaneous wound healing are described, which involves tissue regeneration and repair processes consisting of a sequence of molecular and cellular events. The management of infected wounds is then discussed in detail, covering the roles of traditional medicine practices, novel anti-infective formulations, non-antibiotic approaches, and probiotic bacteria. A section devoted to the interdisciplinary approach to wound care addresses topics including in vitro and in vivo research models, the development of advanced wound dressings, tissue engineering, and the potential applications of bioscaffolds. The authors are all leading researchers in the field. This book is an attempt to showcase current research status and future directions in the area of wound-healing research, which must be of interest to a large group ofreaders and researchers interested in this field.
Häftad, Engelska, 2022
2 574 kr
Skickas inom 10-15 vardagar
This book presents the latest knowledge on both the physiological and the microbiological aspects of wound healing. Fresh insights into the process of cutaneous wound healing are described, which involves tissue regeneration and repair processes consisting of a sequence of molecular and cellular events. The management of infected wounds is then discussed in detail, covering the roles of traditional medicine practices, novel anti-infective formulations, non-antibiotic approaches, and probiotic bacteria. A section devoted to the interdisciplinary approach to wound care addresses topics including in vitro and in vivo research models, the development of advanced wound dressings, tissue engineering, and the potential applications of bioscaffolds. The authors are all leading researchers in the field. This book is an attempt to showcase current research status and future directions in the area of wound-healing research, which must be of interest to a large group ofreaders and researchers interested in this field.
- Nyhet
Inbunden, Engelska, 2026
2 229 kr
Skickas inom 5-8 vardagar
This book delivers authoritative insights into the strategic use of model organisms across microbiology, medicine, and environmental sciences. By presenting microbial systems, conventional animal models, and alternative organisms side by side, it equips researchers with a clear understanding of how each contributes to discovery, testing, and translational applications. From E. coli and S. cerevisiae to primates, nematodes, flies, and zebrafish, the chapters highlight practical strengths and limitations, enabling readers to make informed choices about the most effective platforms for their work.Beyond established models, the volume showcases innovative approaches that are redefining research practice. Humanized animals, 3D printing, and organ-on-chip technologies are examined alongside ethical and regulatory considerations, offering a multidimensional perspective that bridges biology, pharmacy, toxicology, and applied sciences. Specialists will find in this collection not only a comprehensive reference but also a forward-looking resource that enhances their ability to design impactful studies while navigating evolving scientific and regulatory landscapes.
- Nyhet
E-bok
Engelska, 20262 741 kr
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This book delivers authoritative insights into the strategic use of model organisms across microbiology, medicine, and environmental sciences. By presenting microbial systems, conventional animal models, and alternative organisms side by side, it equips researchers with a clear understanding of how each contributes to discovery, testing, and translational applications. From E. coli and S. cerevisiae to primates, nematodes, flies, and zebrafish, the chapters highlight practical strengths and limitations, enabling readers to make informed choices about the most effective platforms for their work. Beyond established models, the volume showcases innovative approaches that are redefining research practice. Humanized animals, 3D printing, and organ-on-chip technologies are examined alongside ethical and regulatory considerations, offering a multidimensional perspective that bridges biology, pharmacy, toxicology, and applied sciences. Specialists will find in this collection not only a comprehensive reference but also a forward-looking resource that enhances their ability to design impactful studies while navigating evolving scientific and regulatory landscapes.
Inbunden, Engelska, 2024
2 463 kr
Skickas inom 10-15 vardagar
This book highlights microbial products and their applications in the health sector. The chapters introduce novel advancements and applications in different pharmaceutical and nutraceutical aspects of applied microbiology. Readers will obtain a detailed overview of the relevance of microbial metabolites to human health and nutrition. Besides knowing the products already developed, they will also get an idea of microbial products currently in the development pipeline and those that are likely to emerge as potential nutraceuticals. Readers will get an interesting and useful perspective on how supplementing food with microbes or their bioactive metabolites can realize the idea of 'food as medicine'. This book introduces the biological activities of various microbial fermentation products, and how they are relevant to mitigating various disease conditions (e.g. neuropathy, diabetes, gut dysbiosis, malnutrition, etc.) in humans. One of the highlights of this volume is the exploration of microbial pigments as potential substitutes for synthetic colorants, offering safer and more sustainable alternatives for the food and healthcare industries. The book has equivalent contributions from experts in academia and industry to fill the communication gap between them. Through this book, readers will gain valuable insights into the historical perspectives, contemporary impacts, and future prospects of microbial applications in health and nutrition. From food preservation to biopharmaceutical production, the potential of microbial products to revolutionize our approach to health and wellness is undeniable.
E-bok
Engelska, 20243 251 kr
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This book highlights microbial products and their applications in the health sector. The chapters introduce novel advancements and applications in different pharmaceutical and nutraceutical aspects of applied microbiology. Readers will obtain a detailed overview of the relevance of microbial metabolites to human health and nutrition. Besides knowing the products already developed, they will also get an idea of microbial products currently in the development pipeline and those that are likely to emerge as potential nutraceuticals. Readers will get an interesting and useful perspective on how supplementing food with microbes or their bioactive metabolites can realize the idea of ''food as medicine''. This book introduces the biological activities of various microbial fermentation products, and how they are relevant to mitigating various disease conditions (e.g. neuropathy, diabetes, gut dysbiosis, malnutrition, etc.) in humans. One of the highlights of this volume is the exploration of microbial pigments as potential substitutes for synthetic colorants, offering safer and more sustainable alternatives for the food and healthcare industries. The book has equivalent contributions from experts in academia and industry to fill the communication gap between them. Through this book, readers will gain valuable insights into the historical perspectives, contemporary impacts, and future prospects of microbial applications in health and nutrition. From food preservation to biopharmaceutical production, the potential of microbial products to revolutionize our approach to health and wellness is undeniable.
Häftad, Engelska, 2025
2 463 kr
Skickas inom 10-15 vardagar
This book highlights microbial products and their applications in the health sector. The chapters introduce novel advancements and applications in different pharmaceutical and nutraceutical aspects of applied microbiology. Readers will obtain a detailed overview of the relevance of microbial metabolites to human health and nutrition. Besides knowing the products already developed, they will also get an idea of microbial products currently in the development pipeline and those that are likely to emerge as potential nutraceuticals. Readers will get an interesting and useful perspective on how supplementing food with microbes or their bioactive metabolites can realize the idea of 'food as medicine'. This book introduces the biological activities of various microbial fermentation products, and how they are relevant to mitigating various disease conditions (e.g. neuropathy, diabetes, gut dysbiosis, malnutrition, etc.) in humans. One of the highlights of this volume is the exploration of microbial pigments as potential substitutes for synthetic colorants, offering safer and more sustainable alternatives for the food and healthcare industries. The book has equivalent contributions from experts in academia and industry to fill the communication gap between them. Through this book, readers will gain valuable insights into the historical perspectives, contemporary impacts, and future prospects of microbial applications in health and nutrition. From food preservation to biopharmaceutical production, the potential of microbial products to revolutionize our approach to health and wellness is undeniable.
Inbunden, Engelska, 2023
3 041 kr
Skickas inom 10-15 vardagar
This book explains the potential value of microbiome and microbiome composition associated with human health and diseases. The opening chapters describe the current state of knowledge regarding the human microbiome structure, function, and diversity. The mechanisms of action and the various putative uses of human microbiome are then examined specific to healthy and disease conditions. Readers will find detailed information on its manipulation of human microbiome studies as well as its applied and translational aspects in the current field. The latest knowledge on probiotics, prebiotics, synbiotics, and postbiotics is presented, and specific cases to date are discussed. This book features knowledge from leading researchers working on different aspects of the human microbiome and its manipulation for better health. Overall, this book is an excellent source for microbiome researchers and students from all levels seeking the most up-to-date advancements in the field and also to point toward the future directions.
E-bok
Engelska, 20233 948 kr
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This book explains the potential value of microbiome and microbiome composition associated with human health and diseases. The opening chapters describe the current state of knowledge regarding the human microbiome structure, function, and diversity. The mechanisms of action and the various putative uses of human microbiome are then examined specific to healthy and disease conditions. Readers will find detailed information on its manipulation of human microbiome studies as well as its applied and translational aspects in the current field. The latest knowledge on probiotics, prebiotics, synbiotics, and postbiotics is presented, and specific cases to date are discussed. This book features knowledge from leading researchers working on different aspects of the human microbiome and its manipulation for better health. Overall, this book is an excellent source for microbiome researchers and students from all levels seeking the most up-to-date advancements in the field and also to point toward the future directions.
Engelska, 2023
648 kr
Skickas inom 5-8 vardagar
Häftad, Engelska, 2024
3 041 kr
Skickas inom 10-15 vardagar
This book explains the potential value of microbiome and microbiome composition associated with human health and diseases. The opening chapters describe the current state of knowledge regarding the human microbiome structure, function, and diversity. The mechanisms of action and the various putative uses of human microbiome are then examined specific to healthy and disease conditions. Readers will find detailed information on its manipulation of human microbiome studies as well as its applied and translational aspects in the current field. The latest knowledge on probiotics, prebiotics, synbiotics, and postbiotics is presented, and specific cases to date are discussed. This book features knowledge from leading researchers working on different aspects of the human microbiome and its manipulation for better health. Overall, this book is an excellent source for microbiome researchers and students from all levels seeking the most up-to-date advancements in the field and also to point toward the future directions.