Vijay Kumar Prajapati – författare

Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials.

My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines.

This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens.

Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

Provides in-depth knowledge of vaccine history Covers the development of system vaccinology and their applications revolutionize the vaccine discovery Gives insights to the development of new strategies to design efficacious and safe vaccine molecule Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials Highlights the importance of differential miRNA expression, microbiome after vaccination for human health Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity Aims to understand disease pathogenesis and host responses to infection and vaccination Offers a seamless continuum of scientific discovery and vaccine invention

Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials.My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines.This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens.Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.- Provides in-depth knowledge of vaccine history- Covers the development of system vaccinology and their applications revolutionize the vaccine discovery- Gives insights to the development of new strategies to design efficacious and safe vaccine molecule- Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials- Highlights the importance of differential miRNA expression, microbiome after vaccination for human health- Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial- Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity- Aims to understand disease pathogenesis and host responses to infection and vaccination- Offers a seamless continuum of scientific discovery and vaccine invention

MicroRNA in Human Infectious Diseases offers an overview of the therapeutic and diagnostic role microRNAs can play in treating infectious diseases. Beginning with an introduction on microRNAs and their mechanisms, the book then delves into the therapeutic role of microRNAs in various categories of diseases, including bacterial, viral, and parasitic. A wide range of diseases are explored, including STDs, typhoid, tuberculosis, Dengue fever, Ebola, Covid-19, Malaria, Leishmaniasis, and Lymphatic filariasis. The final section of the book covers microRNA-based system approaches, considering aspects such as web-based tools available for detecting and predicting microRNA targets and the latest technologies for modifying and manipulating microRNAs.This volume explores microRNA across a multitude of conditions and is an ideal reference for those involved in the investigation and development of treatments in this area.

Includes foundational knowledge on microRNAs and the fundamental aspects of its biogenesisExplores the potential role microRNAs can play in therapeutics and diagnostics to treat various infectious diseases, including sexually-transmitted diseases, bacterial diseases, viral infections, and parasitic diseasesFeatures a chapter dedicated to the role of microRNA for therapeutics in respiratory viral infections, such as Covid-19Considers technologies used for manipulating and modifying microRNAs in preparation for applications to treat infectious diseases

MicroRNA in Human Infectious Diseases offers a detailed overview of the therapeutic and diagnostic role microRNAs can play in the treatment of various infectious diseases. Beginning with an introduction on microRNAs and their mechanisms, the book then delves into the therapeutic role of microRNAs in various categories of diseases: bacterial, viral, and parasitic.A wide range of diseases are explored in these sections, including sexually transmitted diseases, typhoid, tuberculosis, Dengue fever, Ebola, Covid-19, Malaria, Leishmaniasis, and Lymphatic filariasis. The final section of the book covers microRNA-based system approaches, considering aspects such as web-based tools available for detecting and predicting microRNA targets, and the latest technologies for modifying and manipulating microRNAs.This volume explores microRNA across a multitude of conditions and is an ideal reference for those involved in the investigation and development of treatments in this area.- Includes foundational knowledge on microRNAs and the fundamental aspects of its biogenesis- Explores the potential role microRNAs can play in therapeutics and diagnostics to treat various infectious diseases, including sexually-transmitted diseases, bacterial diseases, viral infections, and parasitic diseases- Features a chapter dedicated to the role of microRNA for therapeutics in respiratory viral infections, such as Covid-19- Considers technologies used for manipulating and modifying microRNAs in preparation for applications to treat infectious diseases

FORMTEXT Immunotherapy is emerging as a novel and reliable therapeutic technique for treating diseases such as autoimmunity, HIV/AIDS, allergy and cancers. Immunotherapy change or modulate our immune system functionalization and activate it to kill pathogen infected cells or affected cells. Development in the field of Immunology, Molecular Biology, and Pharmaceutical Sciences empower the immune system for protecting us agaist number of pathogenic infections. This volume consisit of the chapters from the different stalwarts of the field coveriing the topic such as Immunotherapy past and present, Oncolytic virus based therapy, CAR-T cell therapy, antibody engineering, adjuvant engineering etc. Chapters covered in this volume discuss the immunological translational research in the field of human cancer, parasitic and infectiouds diseases. This volume incudes the chapter describing the tools developed by scientist to engineers safe and effective antibody which can be used as powerful medicine durig human disease conditions. This volume will reflect the secret of biological sciences and technology in the field on immunology to develop safe and efficacious immune molecules based magic bullet to provide absolute cure. This volume will be helpful to the early career researchers and students working in the field of basic and applied immunological sciences.ImmunotherapyMonoclonal antibodyCytokines

Immunology for Engineers, Volume 140 consists of chapters from stalwarts of the field, covering topics such as antibody engineering, adjuvant requirement and its methodology for assessment, and the need to develop immunotherapy, etc. Chapters covered in this volume discuss Current Status and Future Prospective of Breast Cancer Immunotherapy, Engineering high affinity antigen binders- beyond antibodies, Platelets and Inter-Cellular Communication in Immune Responses: Dialogue with both Professional and Non-Professional Immune Cells, Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapy: A boon for cancer-free life, and Molecular insights and promise of Oncolytic Virus based Immunotherapy.Presents the latest in immunological engineeringDelves into timely topics such as antibody engineeringCovers vaccine engineering amongst many other important topics

Microbiome and Tumorigenesis in Different Cancers delves into the intricate relationship between the human microbiome and various health conditions, with a particular focus on cancer. It is divided into five parts, each addressing a critical aspect of microbiome research and its implications for health and disease. In 4 parts the book provides a foundational understanding of the human microbiome, examines the dual role of the microbiome in cancer development, discusses the role of dysbiosis in gastrointestinal, skin, oral, lung, genitourinary, and hematological malignancies and gives an overview of the methodologies used to study the microbiome. The final part explores the emerging field of pharmacomicrobiomics, focusing on the interaction between the microbiome and cancer therapies. This book serves as a valuable resource for researchers, clinicians, and students interested in understanding the complex interplay between the microbiome and cancer, offering insights into potential therapeutic strategies and future directions in microbiome research.Offers an in-depth exploration of the human microbiome, including its composition, diversity, and the concept of dysbiosisIs dedicated to understanding how the microbiome influences cancer development, progression, and treatmentIncludes detailed chapters on the latest methodologies for studying the microbiome, such as high-throughput sequencing, bioinformatics tools, and various profiling techniquesAddresses practical aspects like sampling methods and ethical considerations